Volume 33, No 10, Oct 2023

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 33 Issue 10, October 2023: 743-744

RESEARCH HIGHLIGHTS

Dancing with DNA: AID embraces flexible partners

Jianshu Wang , David G. Schatz^*

Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA
Correspondence: David G. Schatz(david.schatz@yale.edu)

Wang et al. reveal that mesoscale DNA sequences containing flexible pyrimidine-pyrimidine dimers determine preferential hypermutability by facilitating binding to positively-charged surface patches of AID.

https://doi.org/10.1038/s41422-023-00823-1

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