Volume 34, No 1, Jan 2024

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 34 Issue 1, January 2024: 5-6

RESEARCH HIGHLIGHTS

Swiss army knife T cell: one T cell many tumor targets

Abdulla Berjis^1,2 , Deeksha Muthumani^1,2 , Neil C. Sheppard^1,3 , Carl H. June^1,3,*

¹Center for Cellular Immunotherapies, Philadelphia, PA, USA
²School of Engineering and Applied Science, Philadelphia, PA, USA
³Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA
Correspondence: Carl H. June(cjune@upenn.edu)

T cell immunotherapies have revolutionized the treatment of many types of cancer; however, the exact mechanisms of some of these therapies remain unknown. In a recent study published in Cell, Dolton et al. found that in a melanoma patient who had a successful immunotherapy treatment, T cells can recognize not 1 but 3 tumor-associated antigens.

https://doi.org/10.1038/s41422-023-00871-7

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