Volume 34, No 6, Jun 2024

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 34 Issue 6, June 2024: 405-406

RESEARCH HIGHLIGHTS

The hidden face of GluD1 at inhibitory synapses

Masayuki Itoh , Michisuke Yuzaki^*

Department of Neurophysiology, Keio University School of Medicine, Tokyo, Japan
Correspondence: Michisuke Yuzaki(myuzaki@keio.jp)

The δ-glutamate receptor (GluD), comprising GluD1 and GluD2, is a member of the ionotropic glutamate receptor family, playing a pivotal role in the development and maturation of both excitatory and inhibitory synapses. In a recent study in Science, Piot et al. revealed that GABA, as well as D-Ser, binds to GluD1 to regulate long-term plasticity at inhibitory synapses in the hippocampus, revealing yet another face of GluD receptors.

https://doi.org/10.1038/s41422-024-00931-6

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