Volume 34, No 4, Apr 2024

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 34 Issue 4, April 2024: 327-330   |  Open Access

LETTERS TO THE EDITOR

Base editing effectively prevents early-onset severe cardiomyopathy in Mybpc3 mutant mice

Shuo Wu^1,† , Ping Yang^1,† , Zilong Geng^1,† , Yige Li^1,† , Zhizhao Guo¹ , Yingmei Lou¹ , Shasha Zhang¹ , Junhao Xiong¹ , Huan Hu¹ , Xiaoling Guo² , William T. Pu^3,4 , Yan Zhang^5,* , Dan Zhu^1,* , Bing Zhang^1,*

¹Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Shanghai Chest Hospital, Engineering Research Center of Techniques and Instruments for Diagnosis and Treatment of Congenital Heart Disease, Institute of Developmental and Regenerative Medicine, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
²Basic Medical Research Center, the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
³Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA
⁴Harvard Stem Cell Institute, Harvard University, Boston, MA, USA
⁵School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China
^†These authors contributed equally: Shuo Wu, Ping Yang, Zilong Geng, Yige Li
Correspondence: Yan Zhang(yanzhang@sjtu.edu.cn)Dan Zhu(zhudanmd@163.com)Bing Zhang(bingzhang@sjtu.edu.cn)

https://doi.org/10.1038/s41422-024-00930-7

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