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Volume 34, No 6, Jun 2024

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 34 Issue 6, June 2024: 401-402

RESEARCH HIGHLIGHTS

A tale of two calcium channels: structural pharmacology of Cav2.1 and Cav3.2

Laurent Ferron , Gerald W. Zamponi*

Hotchkiss Brain Institute and Alberta Children’s Hospital Research Institute, Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada
Correspondence: Gerald W. Zamponi(zamponi@ucalgary.ca)

Voltage-gated calcium channels control a plethora of physiological and pathophysiological processes and are important targets for therapeutic intervention into conditions such as epilepsy, pain, and cardiovascular diseases. Two elegant studies published in Cell Research provide structural insights into the molecular pharmacology of P/Q-type and T-type calcium channels.


https://doi.org/10.1038/s41422-024-00961-0

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