Volume 34, No 9, Sep 2024

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 34 Issue 9, September 2024: 603-604

RESEARCH HIGHLIGHTS

DALT: the brain’s border patrol

Jang Hyun Park^1,2 , Jenolyn F. Alexander^1,2 , Leon C. D. Smyth^1,2 , Jonathan Kipnis^1,2,*

¹Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA
²Department of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA
Correspondence: Jonathan Kipnis(kipnis@wustl.edu)

Mucosal-associated lymphoid tissues are the immune structures that rapidly initiate local immune responses; the dura mater is the outermost layer of the meninges covering and connecting central nervous system (CNS) with the periphery. In a recent work published in Nature, Fitzpatrick et al. demonstrate the presence of dura-associated lymphoid tissue, which forms during early postnatal development and expands following infections to protect the fenestrated dural vasculature and prevent pathogen entry into the CNS.

https://doi.org/10.1038/s41422-024-00976-7

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