Volume 34, No 12, Dec 2024

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 34 Issue 12, December 2024: 818-819

RESEARCH HIGHLIGHTS

A cross-species foundation model for single cells

Korbinian Traeuble^1,2 , Matthias Heinig^1,2,3,*

¹Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany
²Department of Computer Science, TUM School of Computation, Information and Technology, Technical University of Munich, Garching, Germany
³German Center for Cardiovascular Research, partner site Munich Heart Alliance, Berlin, Germany
Correspondence: Matthias Heinig(matthias.heinig@helmholtz-munich.de)

Foundation models in transcriptomics have gained attention due to their ability to generalize across tasks with limited labeled data. GeneCompass builds upon these models by incorporating prior biological knowledge and datasets from both human and mouse cells, enhancing its capacity for cross-species analysis and advancing the field of single-cell transcriptomics.

https://doi.org/10.1038/s41422-024-01045-9

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