Volume 35, No 4, Apr 2025

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 35 Issue 4, April 2025: 231-232

RESEARCH HIGHLIGHTS

Raptin, a novel brain hormone links sleep health to body weight gain

Leonie Cabot^1,2 , Henning Fenselau^1,2,3,*

¹Research Group Synaptic Transmission in Energy Homeostasis, Max Planck Institute for Metabolism Research, Cologne, Germany
²Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne, Cologne, Germany
³Policlinic for Endocrinology, Diabetes, and Preventive Medicine, University Hospital Cologne, Cologne, Germany
Correspondence: Henning Fenselau(henning.fenselau@sf.mpg.de)

Accumulating evidence suggests that poor sleep health is associated with an increased risk to develop obesity. Recently, Xie and colleagues have identified a novel hormone, raptin, which is secreted from the brain during sleep to decrease body weight gain by regulating food intake.

https://doi.org/10.1038/s41422-025-01083-x

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