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Submit Manuscript Volume 35, No 8, Aug 2025
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 35 Issue 8, August 2025: 545-546
New insights into how parental worms protect their offspring
Chenming Zeng , Eric A. Miska*
Department of Biochemistry, University of Cambridge, Cambridge, UKParental exposure of Caenorhabditis elegans to pathogens can protect offspring against similar threats, but the bacterial cues and intergenerational signals underlying this response remain poorly understood. A recent study in Cell revealed a novel mechanism of intergenerational protection against natural pathogens, facilitated by the cyanoalanine synthase CYSL-2 and its detoxification intermediate.
https://doi.org/10.1038/s41422-025-01094-8