Volume 36, No 3, Mar 2026

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 36 Issue 3, March 2026: 233-236

LETTERS TO THE EDITOR

Efficient chemical reprogramming of human T cells to pluripotent stem cells

Yanglu Wang^1,† , Fangqi Peng^2,† , Ruoqi Cheng^2,3,† , Jingran Zeng^1,† , Weizhen Zeng^2,† , Jingping Mao² , Xiaodi Fu² , Guanxian Chen² , Tianxing Liu² , Zhihan Yang² , Cheng Li³ , Bei Liu^2,4,* , Jingyang Guan^1,* , Lin Cheng^2,* , Hongkui Deng^2,5,*

¹Department of Molecular and Cellular Pharmacology, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
²MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences and MOE Engineering Research Center of Regenerative Medicine, School of Basic Medical Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China
³School of Life Sciences, Center for Bioinformatics, Center for Statistical Science, Peking University, Beijing, China
⁴BeiCell Therapeutics, Beijing, China
⁵Changping Laboratory, Beijing, China
^†These authors contributed equally: Yanglu Wang, Fangqi Peng, Ruoqi Cheng, Jingran Zeng, Weizhen Zeng
Correspondence: Bei Liu(sweethoneybeibei@163.com)Jingyang Guan(guanjingyang@hsc.pku.edu.cn)Lin Cheng(lin_cheng@pku.edu.cn)Hongkui Deng(hongkui_deng@pku.edu.cn)

https://doi.org/10.1038/s41422-025-01216-2

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