Volume 36, No 5, May 2026
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 36 Issue 5, May 2026: 377-380 | Open Access
LETTERS TO THE EDITOR
IRES–cargo interplay structurally modulates circular RNA translation
Youkui Huang1,† , Yao-Qi Chen2,† , Si-Yu Lou1,† , Xiang Gao3,† , Yu-Xin Liu1 , Yu-Lu Zhang3 , Fang Nan1,2 , Ling-Ling Chen1,4,5,6,* , Li Yang2,*
1State Key Laboratory of RNA Innovation, Science and Engineering, New Cornerstone Science Laboratory, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China
2Center for Molecular Medicine, Children’s Hospital of Fudan University and Shanghai Key Laboratory of Medical Epigenetics, International Laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, China
3Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China
4School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
5School of Life Science and Technology, ShanghaiTech University, Shanghai, China
6Shanghai Academy of Natural Sciences (SANS), Shanghai, China
†These authors contributed equally: Youkui Huang, Yao-Qi Chen, Si-Yu Lou, Xiang Gao
Correspondence: Ling-Ling Chen(linglingchen@sibcb.ac.cn)Li Yang(liyang_fudan@fudan.edu.cn)
https://doi.org/10.1038/s41422-026-01233-9
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