RESEARCH HIGHLIGHTS

IDH1 mutant structures reveal a mechanism of dominant inhibition

Shimin Zhao and Kun-Liang Guan
Cell Research (2010) 20:1279-1281. doi:10.1038/cr.2010.160; published online 16 November 2010
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Hot stuff: thyroid hormones and AMPK

D Grahame Hardie
Cell Research (2010) 20:1282-1284. doi:10.1038/cr.2010.153; published online 9 November 2010
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CRY links the circadian clock and CREB-mediated gluconeogenesis

Megumi Hatori and Satchidananda Panda
Cell Research (2010) 20:1285-1288. doi:10.1038/cr.2010.152; published online 9 November 2010
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ORIGINAL ARTICLES

Chemical probing reveals insights into the signaling mechanism of inflammasome activation

Yi-Nan Gong, Xiaoming Wang, Jiayi Wang, Zhenxiao Yang, Shan Li, Jieling Yang, Liping Liu, Xiaoguang Lei and Feng Shao
Cell Research (2010) 20:1289-1305. doi:10.1038/cr.2010.135; published online 21 September 2010
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Smad2 mediates Activin/Nodal signaling in mesendoderm differentiation of mouse embryonic stem cells

Teng Fei, Shanshan Zhu, Kai Xia, Jianping Zhang, Zhongwei Li, Jing-Dong J Ha and Ye-Guang Chen
Cell Research (2010) 20:1306-1318. doi:10.1038/cr.2010.158; published online 16 November 2010
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VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

Luqing Zhang, Fei Zhou, Wencan Han, Bin Shen, Jincai Luo, Masabumi Shibuya and Yulong He
Cell Research (2010) 20:1319-1331. doi:10.1038/cr.2010.116; published online 10 August 2010
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The Arabidopsis PRC1-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth

Donghong Chen, Anne Molitor, Chunlin Liu and Wen-Hui Shen
Cell Research (2010) 20:1332-1344. doi:10.1038/cr.2010.151; published online 9 November 2010
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A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes

Yi Zhang, Mo-bin Cheng, Yan-jun Zhang, Xin Zhong, Hui Dai, Li Yan, Ning-hua Wu, Ye Zhang and Yu-fei Shen
Cell Research (2010) 20:1345-1360. doi:10.1038/cr.2010.155; published online 16 November 2010
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Structural basis of immunosuppression by the therapeutic antibody daclizumab

Hui Yang, Jianchuan Wang, Jiamu Du, Chen Zhong, Dapeng Zhang, Huaizu Guo, Yajun Guo and Jianping Ding
Cell Research (2010) 20:1361-1371. doi:10.1038/cr.2010.130; published online 7 September 2010
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Physiological levels of ATP negatively regulate proteasome function

Hongbiao Huang, Xiaoyan Zhang, Shujue Li, Ningning Liu, Wen Lian, Emily McDowell, Ping Zhou, Canguo Zhao, Haiping Guo, Change Zhang, Changshan Yang, Guangmei Wen, Xiaoxian Dong, Li Lu, Ningfang Ma, Weihua Dong, Q. Ping Dou, Xuejun Wang and Jinbao Liu
Cell Research (2010) 20:1372-1385. doi:10.1038/cr.2010.123; published online 31 August 2010
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LETTERS TO THE EDITOR

Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin

Xia Ding, Feng Yan, Phil Yao, Zhihong Yang, Weihong Wan, Xiwei Wang, Jing Liu, Xinjiao Gao, Ariane Abrieu, Tongge Zhu, Jiancun Zhang, Zhen Dou and Xuebiao Yao
Cell Research (2010) 20:1386-1389. doi:10.1038/cr.2010.167; published online 30 November 2010
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TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine

Haikuo Zhang, Xin Zhang, Erin Clark, Michelle Mulcahey, Stephen Huang and Yujiang Geno Shi
Cell Research (2010) 20:1390-1393. doi:10.1038/cr.2010.156; published online 16 November 2010
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