EDITORIAL

Gerogenes and gerosuppression: the pillars of precision geromedicine

Carlos López-Otín, Andrea B. Maier, Guido Kroemer
https://doi.org/10.1038/s41422-024-00977-6
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RESEARCH HIGHLIGHTS

Immunotherapy for atherosclerosis by targeting pro-inflammatory T cells

Amir Khan, Klaus Ley
https://doi.org/10.1038/s41422-024-00955-y
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Complement(ing) the microbiome in infants through breastmilk

Samuel P. Nobs, Eran Elinav
https://doi.org/10.1038/s41422-024-00944-1
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Network-level time computations in the suprachiasmatic nucleus

Natalie Ness, Marco Brancaccio
https://doi.org/10.1038/s41422-024-00969-6
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IS607 TnpB is a hypercompact RNA-guided DNA endonuclease

Hui Yang, Dinshaw J. Patel
https://doi.org/10.1038/s41422-024-00973-w
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Metabolic engineering of the paclitaxel anticancer drug

Audrey Oudin, Nicolas Papon, Vincent Courdavault
https://doi.org/10.1038/s41422-024-00950-3
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MRE11 mobilizes CGAS and drives ZBP1-dependent necroptosis

Manuel Beltrán-Visiedo, Siddharth Balachandran, Lorenzo Galluzzi
https://doi.org/10.1038/s41422-024-00939-y
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REVIEW ARTICLE

Past, present, and future of cell replacement therapy for parkinson’s disease: a novel emphasis on host immune responses

Tae-Yoon Park, Jeha Jeon, Young Cha, Kwang-Soo Kim
https://doi.org/10.1038/s41422-024-00971-y
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ORIGINAL ARTICLES

System-level time computation and representation in the suprachiasmatic nucleus revealed by large-scale calcium imaging and machine learning

Zichen Wang, Jing Yu, Muyue Zhai, Zehua Wang, Kaiwen Sheng, Yu Zhu, Tianyu Wang, Mianzhi Liu, Lu Wang, Miao Yan, Jue Zhang, Ying Xu, Xianhua Wang, Lei Ma, Wei Hu, Heping Cheng
https://doi.org/10.1038/s41422-024-00956-x
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ANT2 functions as a translocon for mitochondrial cross-membrane translocation of RNAs

Pengcheng Wang, Lixiao Zhang, Siyi Chen, Renjian Li, Peipei Liu, Xiang Li, Hongdi Luo, Yujia Huo, Zhirong Zhang, Yiqi Cai, Xu Liu, Jinliang Huang, Guangkeng Zhou, Zhe Sun, Shanwei Ding, Jiahao Shi, Zizhuo Zhou, Ruoxi Yuan, Liang Liu, Sipeng Wu, Geng Wang
https://doi.org/10.1038/s41422-024-00978-5
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LETTERS TO THE EDITOR

Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation

Xianwen Ye, Zixuan Huang, Yi Li, Mengjiao Wang, Wanyu Meng, Maojian Miao, Jingdong Cheng
https://doi.org/10.1038/s41422-024-00962-z
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Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2

Lingyun Xia, Yuanyuan Zhang, Qiang Zhou
https://doi.org/10.1038/s41422-024-00958-9
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Structural and functional evidence that GPR30 is not a direct estrogen receptor

Heng Liu, Shimeng Guo, Antao Dai, Peiyu Xu, Xin Li, Sijie Huang, Xinheng He, Kai Wu, Xinyue Zhang, Dehua Yang, Xin Xie, H. Eric Xu
https://doi.org/10.1038/s41422-024-00963-y
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