RESEARCH HIGHLIGHTS

A matter of energy stress: p38β meets mTORC1

Adem Kalender, Anand Selvaraj and George Thomas
Cell Research (2011) 21:859-861. doi:10.1038/cr.2011.65; published online 12 April 2011
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When inordinate tissue growth is beneficial: Improving silk production by increasing silk gland size

Xavier Bellés
Cell Research (2011) 21:862-863. doi:10.1038/cr.2011.68; published online 12 April 2011
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MicroRNA links obesity and impaired glucose metabolism

Koh Ono
Cell Research (2011) 21:864-866. doi:10.1038/cr.2011.78; published online 10 May 2011
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REVIEWS

Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy

Yanfen Liu and Yihong Ye
Cell Research (2011) 21:867-883. doi:10.1038/cr.2011.75; published online 3 May 2011
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ORIGINAL ARTICLES

Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics

Jiekai Chen*, Jing Liu*, You Chen, Jiaqi Yang, Jing Chen, He Liu, Xiangjie Zhao, Kunlun Mo, Hong Song, Lin Guo, Shilong Chu, Deping Wang, Ke Ding and Duanqing Pei
Cell Research (2011) 21:884-894. doi:10.1038/cr.2011.51; published online 29 March 2011
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A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response

Suzanne Paz, Myriam Vilasco, Steven J Werden, Meztli Arguello, Deshanthe Joseph-Pillai, Tiejun Zhao, Thi Lien-Anh Nguyen, Qiang Sun, Eliane F Meurs, Rongtuan Lin and John Hiscott
Cell Research (2011) 21:895-910. doi:10.1038/cr.2011.2; published online 4 January 2011
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Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells

Jungmook Lyu, Eek-hoon Jho and Wange Lu
Cell Research (2011) 21:911-921. doi:10.1038/cr.2011.47; published online 22 March 2011
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Aquaporin3 is a sperm water channel essential for postcopulatory sperm osmoadaptation and migration

Qi Chen, Hongying Peng, Li Lei, Ying Zhang, Haibin Kuang, Yujing Cao, Qi-xian Shi, Tonghui Ma and Enkui Duan
Cell Research (2011) 21:922-933. doi:10.1038/cr.2010.169; published online 7 December 2010
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Ras1^CA overexpression in the posterior silk gland improves silk yield

Li Ma, Hanfu Xu, Jinqi Zhu, Sanyuan Ma, Yan Liu, Rong-Jing Jiang, Qingyou Xia and Sheng Li
Cell Research (2011) 21:934-943. doi:10.1038/cr.2011.36; published online15 March 2011
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Cisplatin ototoxicity involves cytokines and STAT6 signaling network

Hyung-Jin Kim, Gi-Su Oh, Jeong-Han Lee, Ah-Ra Lyu, Hye-Min Ji, Sang-Heon Lee, Jeho Song, Sung-Joo Park, Yong-Ouk You, Jeong-Dug Sul, Channy Park, Sang-Young Chung, Sung-Kyun Moon, David J Lim, Hong-Seob So and Raekil Park
Cell Research (2011) 21:944-956. doi:10.1038/cr.2011.27; published online 22 February 2011
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The endoplasmic reticulum-associated degradation is necessary for plant salt tolerance

Lijing Liu, Feng Cui, Qingliang Li, Bojiao Yin, Huawei Zhang, Baoying Lin, Yaorong Wu, Ran Xia, Sanyuan Tang and Qi Xie
Cell Research (2011) 21:957-969. doi:10.1038/cr.2010.181; published online 28 December 2010
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Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis

>Hongjiang Li, Deshu Lin, Pankaj Dhonukshe, Shingo Nagawa, Dandan Chen, Jiri Friml, Ben Scheres, Hongwei Guo and Zhenbiao Yang
Cell Research (2011) 21:970-978. doi:10.1038/cr.2011.49; publishe online 22 March 2011
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LETTERS TO THE EDITOR

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

Dongshan Yang, Huaqiang Yang, Wei Li, Bentian Zhao, Zhen Ouyang, Zhaoming Liu, Yu Zhao, Nana Fan, Jun Song, Jiangtian Tian, Feng Li, Jifeng Zhang, Lin Chang, Duanqing Pei, Y Eugene Chen and Liangxue Lai
Cell Research (2011) 21:979-982. doi:10.1038/cr.2011.70; published online 19 April 2011
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The oxygen sensor PHD3 limits glycolysis under hypoxia via direct binding to pyruvate kinases

Nan Chen, Oliver Rinner, Dominika Czernik, Katarzyna J Nytko, Dan Zheng, Daniel P Stiehl, Nicola Zamboni, Matthias Gstaiger and Christian Frei

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Human peripheral blood-born hematosphere as a niche for hematopoietic stem cell expansion

Jin Hur, Jonghanne Park, Sang Eun Lee, Chang-Hwan Yoon, Jae Hee Jang, Ji Min Yang, Tae-Kyu Lee, Jae-Il Choi, Han-Mo Yang, Eun Ju Lee, Hyun-Jai Cho, Hyun-Jae Kang, Byung-Hee Oh, Young-Bae Park and Hyo-Soo Kim
Cell Research (2011) 21:987-990. doi:10.1038/cr.2011.69; published online 12 April 2011
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