RESEARCH HIGHLIGHTS

Sodium-activated macrophages: the salt mine expands

Liliana E Lucca and David A Hafler
10.1038/cr.2015.91
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Cancer immunotherapy: exploiting neoepitopes

Michael Platten and Rienk Offringa
10.1038/cr.2015.66
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rsPSCs: A new type of pluripotent stem cells

Uri Weissbein and Nissim Benvenisty
10.1038/cr.2015.73
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A frightening thought: Neuronal activity enhances tumor growth

Emily G Thompson and Harald Sontheimer
10.1038/cr.2015.65
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ORIGINAL ARTICLES

High salt primes a specific activation state of macrophages, M(Na)

Wu-Chang Zhang, Xiao-Jun Zheng, Lin-Juan Du, Jian-Yong Sun, Zhu-Xia Shen, Chaoji Shi, Shuyang Sun, Zhiyuan Zhang, Xiao-qing Chen, Mu Qin, Xu Liu, Jun Tao, Lijun Jia, Heng-yu Fan, Bin Zhou, Ying Yu, Hao Ying, Lijian Hui, Xiaolong Liu, Xianghua Yi, Xiaojing Liu, Lanjing Zhang and Sheng-Zhong Duan
10.1038/cr.2015.87
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DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination

Weihua Qin, Patricia Wolf, Nan Liu, Stephanie Link, Martha Smets, Federica La Mastra, Ignasi Forné, Garwin Pichler, David Hörl, Karin Fellinger, Fabio Spada, Ian Marc Bonapace, Axel Imhof, Hartmann Harz and Heinrich Leonhardt
10.1038/cr.2015.72
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An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells

Hui Qian, Xing Deng, Zhao-Wei Huang, Ji Wei, Chen-Hong Ding, Ren-Xin Feng, Xin Zeng, Yue-Xiang Chen, Jin Ding, Lei Qiu, Zhen-Lin Hu, Xin Zhang, Hong-Yang Wang, Jun-Ping Zhang and Wei-Fen Xie
10.1038/cr.2015.84
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Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction

Xiao-E Jia, Ke Ma, Tao Xu, Lei Gao, Shuang Wu, Cong Fu, Wenjuan Zhang, Zhizhang Wang, Kaiyu Liu, Mei Dong, Changbin Jing, Chunguang Ren, Zhiwei Dong, Yi Chen, Yi Jin, Qiuhua Huang, Xing Chang, Min Deng1, Li Li, Lingfei Luo, Jun Zhu, Yongjun Dang, Hung-Chun Chang, Leonard I Zon, Yi Zhou, Saijuan Chen and Weijun Pan
10.1038/cr.2015.81
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Critical role for Orai1 C-terminal domain and TM4 in CRAC channel gating

Raz Palty, Cherise Stanley and Ehud Y Isacoff
10.1038/cr.2015.80
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LETTERS TO THE EDITOR

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

Yan Li, Qiupeng Zheng, Chunyang Bao, Shuyi Li, Weijie Guo, Jiang Zhao, Di Chen, Jianren Gu, Xianghuo He and Shenglin Huang
10.1038/cr.2015.82
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Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation

Rui Gong, Audrey W Hong, Steven W Plouffe, Bin Zhao, Guangbo Liu, Fa-Xing Yu, Yanhui Xu and Kun-Liang Guan
10.1038/cr.2015.88
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