RESEARCH HIGHLIGHTS

Anti-PD1 in the wonder-gut-land

Marie Vetizou, Giorgio Trinchieri
10.1038/cr.2018.12
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REVIEWS

Mitochondrial metabolism and cancer

Paolo Ettore Porporato, Nicoletta Filigheddu, Jose Manuel Bravo-San Pedro, Guido Kroemer, Lorenzo Galluzzi
10.1038/cr.2017.155
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UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication

Andrew Melber , Cole M Haynes
10.1038/cr.2018.16
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m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration

Maria Patron , Hans-Georg Sprenger, Thomas Langer
10.1038/cr.2018.17
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ORIGINAL ARTICLES

Structure of the human activated spliceosome in three conformational states

Xiaofeng Zhang, Chuangye Yan, Xiechao Zhan, Lijia Li, Jianlin Lei, Yigong Shi
10.1038/cr.2018.14
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Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis

Chao Zhang, Weiwei Yi, Fei Li, Xufei Du, Hu Wang, Ping Wu, Chao Peng, Man Luo, Wen Hua, Catherine CL Wong, James J Lee, Wen Li, Zhihua Chen, Songmin Ying, Zhenyu Ju, Huahao Shen
10.1038/cr.2018.2
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Tamoxifen enhances stemness and promotes metastasis of ERα36+ breast cancer by upregulating ALDH1A1 in cancer cells

Qiang Wang, Jun Jiang, Guoguang Ying, Xiao-Qing Xie, Xia Zhang, Wei Xu, Xuemin Zhang, Erwei Song, Hong Bu, Yi-Fang Ping, Xiao-Hong Yao, Bin Wang, Shilei Xu, Ze-Xuan Yan,Yanhong Tai, Baoquan Hu, Xiaowei Qi, Yan-Xia Wang, Zhi-Cheng He, Yan Wang, Ji Ming Wang, You-Hong Cui, Feng Chen, Kun Meng, Zhaoyi Wang, Xiu-Wu Bian
10.1038/cr.2018.15
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Diverse modes of clonal evolution in HBV-related hepatocellular carcinoma revealed by single-cell genome sequencing

Meng Duan, Junfeng Hao, Sijia Cui, Daniel L Worthley, Shu Zhang, Zhichao Wang, Jieyi Shi, Longzi Liu, Xiaoying Wang, Aiwu Ke, Ya Cao, Ruibin Xi, Xiaoming Zhang, Jian Zhou, Jia Fan, Chong Li & Qiang Gao
10.1038/cr.2018.11
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LETTERS TO THE EDITOR

Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore

Tian Tian, Xiaorun Li, Yingying Liu, Chengliang Wang, Xing Liu, Guoqiang Bi, Xuan Zhang, Xuebiao Yao, Z Hong Zhou, Jianye Zang
10.1038/cr.2018.13
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Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing

Xuan Yao, Zhen Liu, Xing Wang, Yan Wang, Yan-Hong Nie, Liang Lai, Ruilin Sun, Linyu Shi, Qiang Sun & Hui Yang
10.1038/cr.2018.9
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Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination

Yiqiang Cui, Yuyu Niu, Jiankui Zhou, Yongchang Chen, Yiwei Cheng, Shangang Li, Zongyong Ai, Chu Chu, Hong Wang, Bo Zheng, Xuejin Chen, Jiahao Sha, Xuejiang Guo, Xingxu Huang & Weizhi Ji
10.1038/cr.2018.10
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CORRIGENDA

Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers

Jian Yan 1, 2, Shi-An A Chen 1, Andrea Local 1, Tristin Liu 1, Yunjiang Qiu 1, Kristel M Dorighi 6, Sebastian Preissl 1,Chloe M Rivera 1, Chaochen Wang 3, Zhen Ye 1, Kai Ge 3, Ming Hu 4, Joanna Wysocka 6, Bing Ren 1, 5
10.1038/cr.2018.18
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