Cell Research

Volume 30 Issue 7, Jul 2020

The main inhibitory neurotransmitter in the brain, GABA, influences neuronal and glial activity in a prolonged manner via GABAB receptor, a prototypical class C GPCR. GABAB receptor is an obligatory heterodimer of two subunits. They perform a complicated “pas de deux” to transduce the extracellular stimuli into cells. See page 564-573 by Chunyou Mao et al. for details.

EDITORIAL

A special review collection on autophagy

Li Yu
https://doi.org/10.1038/s41422-020-0361-2
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RESEARCH HIGHLIGHTS

Ubiquitilated Fanconi ID complex embraces DNA

Yathish Jagadheesh Achar, Marco Foiani
https://doi.org/10.1038/s41422-020-0345-2
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A β-galactosidase kiss of death for senescent cells

Xiaoqian Liu, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Guang-Hui Liu
https://doi.org/10.1038/s41422-020-0325-6
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Secret(ory) revealed: the long-awaited structures of secretory IgA

Andrew B. Herr
https://doi.org/10.1038/s41422-020-0351-4
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Social dominance hierarchy: toward a genetic and evolutionary understanding

Bruce T. Lahn
https://doi.org/10.1038/s41422-020-0347-0
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ILC transdifferentiation: roles in cancer progression

Maryam Ghaedi, Pamela S. Ohashi
https://doi.org/10.1038/s41422-020-0326-5
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ORIGINAL ARTICLES

Cryo-EM structures of inactive and active GABAB receptor

Chunyou Mao, Cangsong Shen, Chuntao Li, Dan-Dan Shen, Chanjuan Xu, Shenglan Zhang, Rui Zhou, Qingya Shen, Li-Nan Chen, Zhinong Jiang, Jianfeng Liu, Yan Zhang
https://doi.org/10.1038/s41422-020-0350-5
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Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

Yusheng Cai, Huanhuan Zhou, Yinhua Zhu, Qi Sun, Yin Ji, Anqi Xue, Yuting Wang, Wenhan Chen, Xiaojie Yu, Longteng Wang, Han Chen, Cheng Li, Tuoping Luo, Hongkui Deng
https://doi.org/10.1038/s41422-020-0314-9
Full Text | PDF | Abstract | Open Access

Regulation of sister chromatid cohesion by nuclear PD-L1

Jia Yu, Bo Qin, Ann M. Moyer, Xinyi Tu, Haidong Dong, Judy C. Boughey, Matthew P. Goetz, Richard Weinshilboum, Zhenkun Lou, Liewei Wang
https://doi.org/10.1038/s41422-020-0315-8
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Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin

Yuxin Wang, Guopeng Wang, Yaxin Li, Qinyu Zhu, Hao Shen, Ning Gao, Junyu Xiao
https://doi.org/10.1038/s41422-020-0336-3
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Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer

Shuo Wang, Yuan Qu, Pengyan Xia, Yi Chen, Xiaoxiao Zhu, Jing Zhang, Guan Wang, Yong Tian, Jianming Ying, Zusen Fan
https://doi.org/10.1038/s41422-020-0312-y
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LETTERS TO THE EDITOR

Cryo-EM structure of human bile salts exporter ABCB11

Liang Wang, Wen-Tao Hou, Li Chen, Yong-Liang Jiang, Da Xu, Linfeng Sun, Cong-Zhao Zhou, Yuxing Chen
https://doi.org/10.1038/s41422-020-0302-0
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The cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes

Ellen Ngar-Yun Poon, Xiao-ling Luo, Sarah E. Webb, Bin Yan ,Rui Zhao, Stanley Chun Ming Wu, Yong Yang , Peng Zhang,Huajun Bai, Jiaofang Shao, Ching Man Chan,Godfrey Chi-Fung Chan, Suk Ying Tsang ,Rebekah L. Gundry , Huang-Tian Yang and Kenneth R. Boheler

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CORRIGENDA

Correction: Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer

Shuo Wang, Yuan Qu, Pengyan Xia, Yi Chen, Xiaoxiao Zhu, Jing Zhang, Guan Wang, Yong Tian, Jianming Ying, Zusen Fan
https://doi.org/10.1038/s41422-020-0352-3
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