RESEARCH HIGHLIGHTS

GABAB receptor pas de deux: insights from high-resolution structures

Yi Jiang, H. Eric Xu
https://doi.org/10.1038/s41422-020-0373-y
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Reprogramming the microenvironment: tricks of tumor-derived astrocytes

Guoxin Zhang, Jeremy N. Rich
https://doi.org/10.1038/s41422-020-0335-4
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Fibroblasts fuel intestinal tumorigenesis

Dingzhi Wang, Raymond N. DuBois
https://doi.org/10.1038/s41422-020-0340-7
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Combating pancreatic cancer during its Rip Van Winkle sleep

Kıvanç Görgülü, Marina Lesina, Hana Algül
https://doi.org/10.1038/s41422-020-0348-z
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REVIEW ARTICLE

Old dogs, new trick: classic cancer therapies activate cGAS

Seoyun Yum, Minghao Li, Zhijian J. Chen
https://doi.org/10.1038/s41422-020-0346-1
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Metabolic signaling in T cells

Justin A. Shyer, Richard A. Flavell, Will Bailis
https://doi.org/10.1038/s41422-020-0379-5
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Immune checkpoint signaling and cancer immunotherapy

Xing He, Chenqi Xu
https://doi.org/10.1038/s41422-020-0343-4
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ORIGINAL ARTICLES

Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques

Chao Shan, Yan-Feng Yao, Xing-Lou Yang, Yi-Wu Zhou, Ge Gao, Yun Peng, Lian Yang, Xue Hu, Jin Xiong, Ren-Di Jiang, Hua-Jun Zhang, Xiao-Xiao Gao, Cheng Peng, Juan Min, Ying Chen, Hao-Rui Si, Jia Wu, Peng Zhou, Yan-Yi Wang, Hong-Ping Wei, Wei Pang, Zheng-Fei Hu, Long-Bao Lv, Yong-Tang Zheng, Zheng-Li Shi, Zhi-Ming Yuan
https://doi.org/10.1038/s41422-020-0364-z
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Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Chunlong Ma, Michael Dominic Sacco, Brett Hurst, Julia Alma Townsend, Yanmei Hu, Tommy Szeto, Xiujun Zhang, Bart Tarbet, Michael Thomas Marty, Yu Chen, Jun Wang
https://doi.org/10.1038/s41422-020-0356-z
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863 genomes reveal the origin and domestication of chicken

Ming-Shan Wang, Mukesh Thakur, Min-Sheng Peng, Yu Jiang, Laurent Alain François Frantz, Ming Li, Jin-Jin Zhang, Sheng Wang, Joris Peters, Newton Otieno Otecko, Chatmongkon Suwannapoom, Xing Guo, Zhu-Qing Zheng, Ali Esmailizadeh, Nalini Yasoda Hirimuthugoda, Hidayat Ashari, Sri Suladari, Moch Syamsul Arifin Zein, Szilvia Kusza, Saeed Sohrabi, Hamed Kharrati-Koopaee, Quan-Kuan Shen, Lin Zeng, Min-Min Yang, Ya-Jiang Wu, Xing-Yan Yang, Xue-Mei Lu, Xin-Zheng Jia, Qing-Hua Nie, Susan Joy Lamont, Emiliano Lasagna, Simone Ceccobelli, Humpita Gamaralalage Thilini Nisanka Gunwardana, Thilina Madusanka Senasige, Shao-Hong Feng, Jing-Fang Si, Hao Zhang, Jie-Qiong Jin, Ming-Li Li, Yan-Hu Liu, Hong-Man Chen, Cheng Ma, Shan-Shan Dai, Abul Kashem Fazlul Haque Bhuiyan, Muhammad Sajjad Khan, Gamamada Liyanage Lalanie Pradeepa Silva, Thi-Thuy Le, Okeyo Ally Mwai, Mohamed Nawaz Mohamed Ibrahim, Megan Supple, Beth Shapiro, Olivier Hanotte, Guojie Zhang, Greger Larson, Jian-Lin Han, Dong-Dong Wu, Ya-Ping Zhang
https://doi.org/10.1038/s41422-020-0349-y
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LETTERS TO THE EDITOR

Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients

Bao-zhong Zhang, Ye-fan Hu, Lin-lei Chen, Thomas Yau, Yi-gang Tong, Jing-chu Hu1, Jian-piao Cai, Kwok-Hung Chan, Ying Dou, Jian Deng, Xiao-lei Wang, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To, Kwok Yung Yuen, Jian-Dong Huang
https://doi.org/10.1038/s41422-020-0366-x
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Distinct stem/progenitor cells proliferate to regenerate the trachea, intrapulmonary airways and alveoli in COVID-19 patients

Yinshan Fang, Helu Liu, Huachao Huang, Haiyan Li, Anjali Saqi, Li Qiang, Jianwen Que
https://doi.org/10.1038/s41422-020-0367-9
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Pulmonary alveolar regeneration in adult COVID-19 patients

Jingyu Chen, Huijuan Wu, Yuanyuan Yu, Nan Tang
https://doi.org/10.1038/s41422-020-0369-7
Full Text | PDF | Abstract | Open Access