RESEARCH HIGHLIGHTS

3D genome encoded by LINE and SINE repeats

Zhengyu Liang, Xiang-Dong Fu
https://doi.org/10.1038/s41422-021-00485-x
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A spatial map out of place

Adrien Peyrache, Adrian J. Duszkiewicz
https://doi.org/10.1038/s41422-021-00478-w
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Panning for brain antigens in dural sinuses

Ania Bogoslowski, Paul Kubes
https://doi.org/10.1038/s41422-021-00502-z
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LETN and NPM1 tango in human nucleoli

Guang Xu, Man Wu, Ling-Ling Chen
https://doi.org/10.1038/s41422-021-00471-3
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To learn something new, do something new

Adam M. P. Miller, Paul W. Frankland
https://doi.org/10.1038/s41422-021-00508-7
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ORIGINAL ARTICLES

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

J. Yuyang Lu, Lei Chang, Tong Li, Ting Wang, Yafei Yin, Ge Zhan, Xue Han, Ke Zhang, Yibing Tao, Michelle Percharde, Liang Wang, Qi Peng, Pixi Yan, Hui Zhang, Xianju Bi, Wen Shao, Yantao Hong, Zhongyang Wu, Runze Ma, Peizhe Wang, Wenzhi Li, Jing Zhang, Zai Chang, Yingping Hou, Bing Zhu, Miguel Ramalho-Santos, Pilong Li, Wei Xie, Jie Na, Yujie Sun, Xiaohua Shen
https://doi.org/10.1038/s41422-020-00466-6
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In vivo self-assembled small RNAs as a new generation of RNAi therapeutics

Zheng Fu, Xiang Zhang, Xinyan Zhou, Uzair Ur-Rehman, Mengchao Yu, Hongwei Liang, Hongyuan Guo, Xu Guo, Yan Kong, Yuanyuan Su, Yangyang Ye, Xiuting Hu, Wei Cheng, Jinrong Wu, Yanbo Wang, Yayun Gu, Sheng-feng Lu, Dianqing Wu, Ke Zen, Jing Li, Chao Yan, Chen-Yu Zhang, Xi Chen
https://doi.org/10.1038/s41422-021-00491-z
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A novel somatosensory spatial navigation system outside the hippocampal formation

Xiaoyang Long, Sheng-Jia Zhang
https://doi.org/10.1038/s41422-020-00448-8
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Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation

Xianteng Wang, Xiaolin Hu, Wanlu Song, Hui Xu, Zhengtao Xiao, Rongyao Huang, Qingran Bai, Fan Zhang, Yongzhen Chen, Yu Liu, Jianhuo Fang, Xin Li, Qin Shen, Haitao Zhao, Xuerui Yang
https://doi.org/10.1038/s41422-020-00458-6
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Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma

Xiaofei Wang, Ran Zhou, Yanzhen Xiong, Lingling Zhou, Xiang Yan, Manli Wang, Fan Li, Chuanxing Xie, Yiming Zhang, Zongyao Huang, Chaoqiong Ding, Kaidou Shi, Weida Li, Yu Liu, Zhongwei Cao, Zhen-Ning Zhang, Shengtao Zhou, Chong Chen, Yan Zhang, Lu Chen, Yuan Wang
https://doi.org/10.1038/s41422-020-00451-z
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BacFlash signals acid-resistance gene expression in bacteria

Di Wu, Wenfeng Qi, Wei Nie, Zhengyuan Lu, Yongxin Ye, Jinghang Li, Tao Sun, Yufei Zhu, Heping Cheng, Xianhua Wang
https://doi.org/10.1038/s41422-020-00431-3
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LETTERS TO THE EDITOR

Structural basis of human α7 nicotinic acetylcholine receptor activation

Yue Zhao, Sanling Liu, Yingxin Zhou, Mengge Zhang, Haopeng Chen, H. Eric Xu, Demeng Sun, Lei Liu, Changlin Tian
https://doi.org/10.1038/s41422-021-00509-6
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Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2

Renhong Yan, Yuanyuan Zhang, Yaning Li, Fangfei Ye, Yingying Guo, Lu Xia, Xinyue Zhong, Ximin Chi, Qiang Zhou
https://doi.org/10.1038/s41422-021-00490-0
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The basis of a more contagious 501Y.V1 variant of SARS-CoV-2

Haolin Liu, Qianqian Zhang, Pengcheng Wei, Zhongzhou Chen, Katja Aviszus, John Yang, Walter Downing, Chengyu Jiang, Bo Liang, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John Kappler, Philippa Marrack, Gongyi Zhang
https://doi.org/10.1038/s41422-021-00496-8
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