RESEARCH HIGHLIGHTS

Breathless cancer cells get fat on glutamine

Dimitrios Anastasiou and Lewis C Cantley
Cell Research (2012) 22:443-446. doi:10.1038/cr.2012.5; published online 3 January 2012
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PKM2: A gatekeeper between growth and survival

Isaac Harris, Susan McCracken and Tak Wah Mak
Cell Research (2012) 22:447-449. doi:10.1038/cr.2011.203; published online 20 December 2011
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CTCF: from insulators to alternative splicing regulation

Alberto R Kornblihtt
Cell Research (2012) 22:450-452. doi:10.1038/cr.2012.22; published online 7 February 2012
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An evolving picture of the interactions between malaria parasites and their host erythrocytes

Thomas E Wellems and Rick M Fairhurst
Cell Research (2012) 22:453-456. doi:10.1038/cr.2012.14; published online 24 January 2012
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REVIEWS

Understanding cancer stem cell heterogeneity and plasticity

Dean G Tang
Cell Research (2012) 22:457-472. doi:10.1038/cr.2012.13; published online 17 January 2012
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ORIGINAL ARTICLES

Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein

Weijiao Huang, Wooyoung Choi, Wanqiu Hu, Na Mi, Qiang Guo, Meisheng Ma, Mei Liu, Yuan Tian, Peilong Lu, Feng-Liang Wang, Haiteng Deng, Lei Liu, Ning Gao, Li Yu and Yigong Shi
Cell Research (2012) 22:473-489. doi:10.1038/cr.2012.24; published online 7 February 2012
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Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization

Iouri Chepelev, Gang Wei, Dara Wangsa, Qingsong Tang and Keji Zhao
Cell Research (2012) 22:490-503. doi:10.1038/cr.2012.15; published online 24 January 2012
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Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system

Rui Tang, Limin Li, Dihan Zhu, Dongxia Hou, Ting Cao, Hongwei Gu, Jing Zhang, Junyuan Chen, Chen-Yu Zhang and Ke Zen
Cell Research (2012) 22:504-515. doi:10.1038/cr.2011.137; published online 23 August 2011
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Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice

Jian Wang, Yao Song, Yan Zhang, Han Xiao, Qiang Sun, Ning Hou, Shuilong Guo, Youliang Wang, Kaiji Fan, Dawei Zhan, Lagabaiyila Zha
Cell Research (2012) 22:516-527. doi:10.1038/cr.2011.132; published online 16 August 2011
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IL-17 response mediates acute lung injury induced by the 2009 Pandemic Influenza A (H1N1) Virus

Chenggang Li, Penghui Yang, Yang Sun, Taisheng Li, Chen Wang, Zhong Wang, Zhen Zou, Yiwu Yan, Wei Wang, Chen Wang, Zho
Cell Research (2012) 22:528-538. doi:10.1038/cr.2011.165; published online 25 October 2011
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p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis

Simon M Schultze, Andreas Mairhofer, Dan Li, Jin Cen, Hartmut Beug, Erwin F Wagner and Lijian Hui
Cell Research (2012) 22:539-550. doi:10.1038/cr.2011.159; published online 27 September 2011
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TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice

Zhidan Luo, Liqun Ma, Zhigang Zhao, Hongbo He, Dachun Yang, Xiaoli Feng, Shuangtao Ma, Xiaoping Chen, Tianqi Zhu, Tingbing Cao
Cell Research (2012) 22:551-564. doi:10.1038/cr.2011.205; published online 20 December 2011
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A network-based gene-weighting approach for pathway analysis

Zhaoyuan Fang, Weidong Tian and Hongbin Ji
Cell Research (2012) 22:565-580. doi:10.1038/cr.2011.149; published online 6 September 2011
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Arabidopsis phosphatidylinositol monophosphate 5-kinase 2 is involved in root gravitropism through regulation of polar auxin transport by affecting the cycling of PIN proteins

Yu Mei, Wen-Jing Jia, Yu-Jia Chu and Hong-Wei Xue
Cell Research (2012) 22:581-597. doi:10.1038/cr.2011.150; published online 6 September 2011
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LETTERS TO THE EDITOR

Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30

Yong Chen, Fang Cao, Bingbing Wan, Yali Dou and Ming Lei
Cell Research (2012) 22:598-602. doi:10.1038/cr.2012.9; published online 10 January 2012
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The E3 ubiquitin ligase MIB1 negatively regulates basal IκBα level and modulates NF-κB activation

Li-Juan Liu, Tian-Tian Liu, Yong Ran, Ying Li, Xiao-Dong Zhang, Hong-Bing Shu and Yan-Yi Wang
Cell Research (2012) 22:603-606. doi:10.1038/cr.2011.199; published online 20 December 2011
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Immunosuppressive exosomes from TGF-β1 gene-modified dendritic cells attenuate Th17-mediated inflammatory autoimmune disease by inducing regulatory T cells

Zhijian Cai, Wei Zhang, Fei Yang, Lei Yu, Zhou Yu, JihHung Pan, Lie Wang, Xuetao Cao and Jianli Wang
Cell Research (2012) 22:607-610. doi:10.1038/cr.2011.196; published online 13 December 2011
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