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ISSN: 1001-0602
EISSN: 1748-7838
2020 impact factor 25.617*
(Clarivate Analytics, 2021)
About the cover
The image tells a fable story, ‘dirty partner’. A wolf and a jackal often do evil things in collusion with each other. In KRAS-driven cancers, KRAS mutations are like wolves and RASON behaves like a jackal. KRAS mutations initiate tumour formation and promote tumour progression which are enhanced by RASON, a novel protein encoded by long non-coding RNA, LINC00673, and overexpressed in tumour to regulate RAS activity. Cover art is contributed by Chao Yan. See page 30–45 by Rongjie Cheng et al. for details.
LETTERS TO THE EDITOR
Repeated vaccination of inactivated SARS-CoV-2 vaccine dampens neutralizing antibodies against Omicron variants in breakthrough infectionRESEARCH HIGHLIGHTS
RASON, a new player in cancer’s Premier LeagueORIGINAL ARTICLES
A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancersLETTERS TO THE EDITOR
Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant
