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Volume 31, No 3, Mar 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
2019 impact factor 20.507*  
(Clarivate Analytics, 2020)

About the cover

Buddha or evil, depends on a blinding flash. Neddylation can switch PTEN from a tumor suppressor (Buddha) to a tumor promoter (evil). See page 291-311 by Ping Xie et al. for details.

Advanced Online Publication: 5 Mar 2021


Structure of human RNA polymerase III elongation complex

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Current Issue: Vol.31 (Mar 2021)


Dalbavancin: novel candidate for COVID-19 treatment
Gephyrin: a scaffold that builds a phase at the inhibitory postsynapses


SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs
Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages
Neddylation of PTEN regulates its nuclear import and promotes tumor development
Gephyrin-mediated formation of inhibitory postsynaptic density sheet via phase separation
Single-cell patterning and axis characterization in the murine and human definitive endoderm
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells


The oncogenomic function of androgen receptor in esophageal squamous cell carcinoma is directed by GATA3
Structure of the mitochondrial TIM22 complex from yeast
Cryo-EM structure of the human mitochondrial translocase TIM22 complex


Author Correction: Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration
Author Correction: Neddylation of PTEN regulates its nuclear import and promotes tumor development