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ISSN: 1001-0602
EISSN: 1748-7838
2016 impact factor 15.606*
(Clarivate Analytics, 2017)
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    Advanced Online Publication: 4 Dec 2018
RESEARCH HIGHLIGHTS
m6A-epitranscriptome modulates memory strength
ADCP1: a novel plant H3K9me2 reader
Engineering 3D genome organization
ORIGINAL ARTICLES
Ubiquitination of Rheb governs growth factor-induced mTORC1 activation OPEN
A novel m6A reader Prrc2a controls oligodendroglial specification and myelination OPEN
Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling
LETTERS TO THE EDITOR
Palmitoylation stabilizes PD-L1 to promote breast tumor growth
    Current Issue: Vol.28 (Dec 2018)
RESEARCH HIGHLIGHTS
ALPK1: innate attraction to the sweetness of bacteria   
New roles for RAD52 in DNA repair   
ORIGINAL ARTICLES
Structures of the human pre-catalytic spliceosome and its precursor spliceosome   
The adult human testis transcriptional cell atlas OPEN   
Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating   
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis OPEN   
Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade OPEN   
LETTERS TO THE EDITOR
Cryo-EM structure of Type III-A CRISPR effector complex   
Structural insights into Cas13b-guided CRISPR RNA maturation and recognition   
CORRIGENDA
Author Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasome   

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