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ISSN: 1001-0602
EISSN: 1748-7838
2016 impact factor 15.606*
(Clarivate Analytics, 2017)
Free Sample Issue
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·  ISSCR International Symposium "Stem Cells: The Next Generation"
·  第六届全国“跨学科蛋白质研究”学术讨论会
·  Editor Position
     E-alerts
 
    Advanced Online Publication: 15 Aug 2017
RESEARCH HIGHLIGHTS
SMAD5 signaling: more than meets the nuclei FREE
ORIGINAL ARTICLES
Ythdc2 is an N 6-methyladenosine binding protein that regulates mammalian spermatogenesis
Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
IPA1 functions as a downstream transcription factor repressed by D53 in strigolactone signaling in rice OPEN
Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation FREE
Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium
    Current Issue: Vol.27 (Aug 2017)
RESEARCH HIGHLIGHTS
Cardiomyocyte proliferation: remove brakes and push accelerators FREE   
Reassembling embryos in vitro from component stem cells FREE   
Repolarizing macrophages improves breast cancer therapy FREE   
It takes two to transport via an elevator   
ORIGINAL ARTICLES
Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells OPEN   
Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2 FREE   
Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair OPEN   
Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters OPEN   
Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function   
Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction FREE   
LETTERS TO THE EDITOR
Clonal analysis reveals remarkable functional heterogeneity during hematopoietic stem cell emergence OPEN   
Polar bodies are efficient donors for reconstruction of human embryos for potential mitochondrial replacement therapy   
RESEARCH HIGHLIGHTS
RIPped for neuroinflammation FREE   

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