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ISSN: 1001-0602
EISSN: 1748-7838
2016 impact factor 15.606*
(Clarivate Analytics, 2017)
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    Advanced Online Publication: 11 Apr 2019
RESEARCH HIGHLIGHTS
Linking vitamin B12 and a trembling disorder
    Current Issue: Vol.29 (Apr 2019)
RESEARCH HIGHLIGHTS
STIM1 is a precise thermo-sensor in skin   
Anti-Zika virus RNAi in neural progenitor cells   
Broken hearts: Iron overload, ferroptosis and cardiomyopathy   
ORIGINAL ARTICLES
Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids   
Structures of the human spliceosomes before and after release of the ligated exon OPEN   
LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition   
Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry OPEN   
Vitamin B12 modulates Parkinson’s disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection   
LETTERS TO THE EDITOR
Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome   
CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys OPEN   
CORRIGENDA
Author Correction: Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors   
Author Correction: Hormones induce the formation of luminal-derived basal cells in the mammary gland   

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