EDITORIAL

A special issue on cancer immunotherapy

Rong-Fu Wang
10.1038/cr.2017.1
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RESEARCH HIGHLIGHT

Origins of rice cytoplasmic male sterility genes

Deborah Charlesworth
10.1038/cr.2016.158
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Research Highlight

Macroautophagy without LC3 conjugation?

Maurizio Renna and David C Rubinsztein
10.1038/cr.2016.143
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RESEARCH HIGHLIGHTS

Hitting the right button: MAVS-mediated defense against HAV infection

Percy A Knolle
10.1038/cr.2016.139
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A new target for differentiation therapy in AML

Peilin Ma, Weihua Song and Jay L Hess
10.1038/cr.2016.130
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REVIEWS

Immune targets and neoantigens for cancer immunotherapy and precision medicine

Rong-Fu Wang and Helen Y Wang
10.1038/cr.2016.155
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Driving gene-engineered T cell immunotherapy of cancer

Laura A Johnson and Carl H June
10.1038/cr.2016.154
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Immunotherapy against cancer-related viruses

Haruko Tashiro and Malcolm K Brenner
10.1038/cr.2016.153
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Dendritic cell-based immunotherapy

Rachel L Sabado, Sreekumar Balan and Nina Bhardwaj
10.1038/cr.2016.157
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Innate immune signaling and regulation in cancer immunotherapy

Leticia Corrales, Vyara Matson, Blake Flood, Stefani Spranger and Thomas F Gajewski
10.1038/cr.2016.149
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Regulatory T cells in cancer immunotherapy

Atsushi Tanaka and Shimon Sakaguchi
10.1038/cr.2016.151
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ORIGINAL ARTICLES

Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding

Miao Gui, Wenfei Song, Haixia Zhou, Jingwei Xu1, Silian Chen, Ye Xiang and Xinquan Wang
10.1038/cr.2016.152
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Multi-step formation, evolution, and functionalization of new cytoplasmic male sterility genes in the plant mitochondrial genomes

Huiwu Tang, Xingmei Zheng, Chuliang Li, Xianrong Xie, Yuanling Chen, Letian Chen, Xiucai Zhao, Huiqi Zheng, Jiajian Zhou, Shan Ye, Jingxin Guo and Yao-Guang Liu
10.1038/cr.2016.115
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LETTERS TO THE EDITOR

Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab

Zhenkun Na, Siok Ping Yeo, Sakshibeedu R Bharath, Matthew W Bowler, Esra Balıkçı, Cheng-I Wang and Haiwei Song
10.1038/cr.2016.77
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Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy

Kefang Liu, Shuguang Tan, Yan Chai, Danqing Chen, Hao Song, Catherine Wei-Hong Zhang, Yi Shi, Jun Liu, Wenjie Tan, Jianxin Lyu, Shan Gao, Jinghua Yan, Jianxun Qi and George F Gao
10.1038/cr.2016.102
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CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells

Xiaojuan Liu, Yongping Zhang, Chen Cheng, Albert W Cheng, Xingying Zhang, Na Li, Changqing Xia, Xiaofei Wei, Xiang Liu and Haoyi Wang
10.1038/cr.2016.142
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Transfer of convalescent serum to pregnant mice prevents Zika virus infection and microcephaly in offspring

Shuo Wang, Shuai Hong, Yong-Qiang Deng, Qing Ye, Ling-Zhai Zhao, Fu-Chun Zhang, Cheng-Feng Qin and Zhiheng Xu
10.1038/cr.2016.144
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