RESEARCH HIGHLIGHTS

The mitokine quest(ion)

Pan Deng and Cole M Haynes
10.1038/cr.2016.138
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Inhibiting macrophage PI3Kγ to enhance immunotherapy

Wei Zheng and Jeffrey W Pollard
10.1038/cr.2016.132
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Codon optimality and mRNA decay

Yuriko Harigaya and Roy Parker
10.1038/cr.2016.127
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Calcium channel structures come of age

Jian Yang
10.1038/cr.2016.126
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ORIGINAL ARTICLES

Type I CRISPR-Cas targets endogenous genes and regulates virulence to evade mammalian host immunity

Rongpeng Li, Lizhu Fang, Shirui Tan, Min Yu, Xuefeng Li, Sisi He, Yuquan Wei, Guoping Li, Jianxin Jiang and Min Wu
10.1038/cr.2016.135
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ORIGINAL ARTICLE

Crystal structures of the TRIC trimeric intracellular cation channel orthologues

Go Kasuya, Masahiro Hiraizumi, Andrés D Maturana, Kaoru Kumazaki, Yuichiro Fujiwara, Keihong Liu, Yoshiko Nakada-Nakura, So Iwata, Keisuke Tsukada, Tomotaka Komori, Sotaro Uemura, Yuhei Goto, Takanori Nakane, Mizuki Takemoto, Hideaki E Kato, Keitaro Yamashita, Miki Wada, Koichi Ito, Ryuichiro Ishitani, Motoyuki Hattori and Osamu Nureki
10.1038/cr.2016.140
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ORIGINAL ARTICLES

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA

Man Zhang, Meng-Xin Zhang, Qiang Zhang, Gao-Feng Zhu, Lei Yuan, Dong-Er Zhang, Qiyun Zhu, Jing Yao, Hong-Bing Shu and Bo Zhong
10.1038/cr.2016.125
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Structural basis for specific self-incompatibility response in Brassica

Rui Ma, Zhifu Han, Zehan Hu, Guangzhong Lin, Xinqi Gong, Heqiao Zhang, June B Nasrallah and Jijie Chai
10.1038/cr.2016.129
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Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis

Lin Zhang, Jianfeng Xiao, Jianrong Xu, Tianran Fu, Zhiwei Cao, Liang Zhu, Hong-Zhuan Chen, Xu Shen, Hualiang Jiang and Liang Zhang
10.1038/cr.2016.136
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LETTERS TO THE EDITOR

Mapping of long-range chromatin interactions by proximity ligation-assisted ChIP-seq

Rongxin Fang, Miao Yu, Guoqiang Li, Sora Chee, Tristin Liu, Anthony D Schmitt and Bing Ren
10.1038/cr.2016.137
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NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish

Jialing Qi, Zhangji Dong, Yunwei Shi, Xin Wang, Yinyin Qin, Yongming Wang and Dong Liu
10.1038/cr.2016.134
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Structural basis for specific recognition of pre-snRNA by Gemin5

Xuhua Tang, Sakshibeedu R Bharath, Shunfu Piao, Vanessa Qianmin Tan, Matthew W Bowler and Haiwei Song
10.1038/cr.2016.133
Full Text | PDF | Abstract | Open Access