RESEARCH HIGHLIGHTS

Proteasomes, caught in the act

Robert J Tomko Jr
10.1038/cr.2017.22
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GABA signaling: a route to new pancreatic β cells in type 1 diabetes?

Guy A Rutter
10.1038/cr.2017.20
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PHB2/prohibitin 2: An inner membrane mitophagy receptor

Vikramjit Lahiri and Daniel J Klionsky
10.1038/cr.2017.23
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New CRISPR-Cas systems discovered

Hui Yang and Dinshaw J Patel
10.1038/cr.2017.21
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ORIGINAL ARTICLES

YTHDF3 facilitates translation and decay of N 6-methyladenosine-modified RNA

Hailing Shi, Xiao Wang, Zhike Lu, Boxuan S Zhao, Honghui Ma, Phillip J Hsu and Chuan He
10.1038/cr.2017.15
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Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2

Ji Liang, Ruixiu Cao, Xiongjun Wang, Yajuan Zhang, Pan Wang, Hong Gao, Chen Li, Fan Yang, Rong Zeng, Ping Wei, Dawei Li, Wenfeng Li and Weiwei Yang
10.1038/cr.2016.159
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Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis

Yongting Luo, Hongxia Duan, Yining Qian, Liqun Feng, Zhenzhen Wu, Fei Wang, Jing Feng, Dongling Yang, Zhihai Qin and Xiyun Yan
10.1038/cr.2017.8
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High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx

Zhanyu Ding, Zhenglin Fu, Cong Xu, Yifan Wang, Yanxing Wang, Junrui Li, Liangliang Kong, Jinhuan Chen, Na Li, Rongguang Zhang and Yao Cong
10.1038/cr.2017.12
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A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations

Xiaoping Han, Hao Yu, Daosheng Huang, Yang Xu, Assieh Saadatpour, Xia Li, Lengmei Wang, Jie Yu, Luca Pinello, Shujing Lai, Mengmeng Jiang, Xueying Tian, Fen Zhang, Yanhong Cen, Yuko Fujiwara, Wei Zhu, Bin Zhou, Tianhua Zhou, Hongwei Ouyang, Jianan Wang, Guo-Cheng Yuan, Shumin Duan, Stuart H Orkin and Guoji Guo
10.1038/cr.2017.17
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Viral effector protein manipulates host hormone signaling to attract insect vectors

Dewei Wu, Tiancong Qi, Wan-Xiang Li, Haixia Tian, Hua Gao, Jiaojiao Wang, Jin Ge, Ruifeng Yao, Chunmei Ren, Xian-Bing Wang, Yule Liu, Le Kang, Shou-Wei Ding and Daoxin Xie
10.1038/cr.2017.2
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The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis

Fang Wang, Wei Song, Hongmei Zhao, Yanni Ma, Yuxia Li, Di Zhai, Jingnan Pi, Yanmin Si, Jiayue Xu, Lei Dong, Rui Su, Mengmeng Zhang, Yong Zhu, Xiaoxia Ren, Fei Miao, Wenjie Liu, Feng Li, Junwu Zhang, Aibin He, Ge Shan, Jingyi Hui, Linfang Wang and Jia Yu
10.1038/cr.2017.26
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LETTERS TO THE EDITOR

A non-viral CRISPR/Cas9 delivery system for therapeutic gene targeting in vivo

Chao Jiang, Miao Mei, Bin Li, Xiurui Zhu, Wenhong Zu, Yujie Tian, Qiannan Wang, Yong Guo, Yizhou Dong and Xu Tan
10.1038/cr.2017.16
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Cytoplasmic m6A reader YTHDF3 promotes mRNA translation

Ang Li, Yu-Sheng Chen, Xiao-Li Ping, Xin Yang, Wen Xiao, Ying Yang, Hui-Ying Sun, Qin Zhu, Poonam Baidya, Xing Wang, Devi Prasad Bhattarai, Yong-Liang Zhao, Bao-Fa Sun and Yun-Gui Yang
10.1038/cr.2017.10
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The glial actin cytoskeleton regulates neuronal ciliogenesis

Hao Zhu, Lianwan Chen, Yihong Yang, Zhiwen Zhu, Xianliang Zhang, Wei Li, Long Miao, Yan Zhang and Guangshuo Ou
10.1038/cr.2016.131
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