RESEARCH HIGHLIGHTS

T(ell)TALE signs of aging

Reshma Taneja and Brian K Kennedy
10.1038/cr.2017.33
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Both sides of the same coin: Rac1 splicing regulating by EGF signaling

Xiang-Dong Fu
10.1038/cr.2017.19
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Making a splash with splicing

Robyn Branicky and Siegfried Hekimi
10.1038/cr.2017.24
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Cancer: a new role for non-canonical Hippo signaling

Jonathan Cooper and Filippo G Giancotti
10.1038/cr.2017.27
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ORIGINAL ARTICLES

Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer

Shicheng Su, Jianyou Liao, Jiang Liu, Di Huang, Chonghua He, Fei Chen, LinBing Yang, Wei Wu, Jianing Chen, Ling Lin, Yunjie Zeng, Nengtai Ouyang, Xiuying Cui, Herui Yao, Fengxi Su, Jian-dong Huang, Judy Lieberman, Qiang Liu and Erwei Song
10.1038/cr.2017.34
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Visualization of aging-associated chromatin alterations with an engineered TALE system

Ruotong Ren, Liping Deng, Yanhong Xue, Keiichiro Suzuki, Weiqi Zhang, Yang Yu, Jun Wu, Liang Sun, Xiaojun Gong, Huiqin Luan, Fan Yang, Zhenyu Ju, Xiaoqing Ren, Si Wang, Hong Tang, Lingling Geng, Weizhou Zhang, Jian Li, Jie Qiao, Tao Xu, Jing Qu and Guang-Hui Liu
10.1038/cr.2017.18
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Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor

Xingdong Guo, Chengsong Yan, Hua Li, Wenmao Huang, Xiaoshan Shi, Min Huang, Yingfang Wang, Weiling Pan, Mingjun Cai, Lunyi Li, Wei Wu, Yibing Bai, Chi Zhang, Zhijun Liu, Xinyan Wang, Xiaohui F Zhang, Chun Tang, Hongda Wang, Wanli Liu, Bo Ouyang, Catherine C Wong, Yi Cao and Chenqi Xu
10.1038/cr.2017.42
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De novo DNA methylation during monkey pre-implantation embryogenesis

Fei Gao, Yuyu Niu, Yi Eve Sun, Hanlin Lu, Yongchang Chen, Siguang Li, Yu Kang, Yuping Luo, Chenyang Si, Juehua Yu, Chang Li, Nianqin Sun, Wei Si, Hong Wang, Weizhi Ji and Tao Tan
10.1038/cr.2017.25
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SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling

Feng Wang, Xing Fu, Peng Chen, Ping Wu, Xiaojuan Fan, Na Li, Hong Zhu, Ting-Ting Jia, Hongbin Ji, Zefeng Wang, Catherine C L Wong, Ronggui Hu and Jingyi Hui
10.1038/cr.2017.7
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Mesenchymal stem cell transplantation in tight-skin mice identifies miR-151-5p as a therapeutic target for systemic sclerosis

Chider Chen, Dandan Wang, Alireza Moshaverinia, Dawei Liu, Xiaoxing Kou, Wenjing Yu, Ruili Yang, Lingyun Sun and Songtao Shi
10.1038/cr.2017.11
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Efficient generation of mice carrying homozygous double-floxp alleles using the Cas9-Avidin/Biotin-donor DNA system

Ming Ma, Fengfeng Zhuang, Xiongbing Hu, Bolun Wang, Xian-Zi Wen, Jia-Fu Ji and Jianzhong Jeff Xi
10.1038/cr.2017.29
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LETTERS TO THE EDITOR

Cryo-EM structure of Nma111p, a unique HtrA protease composed of two protease domains and four PDZ domains

Li Zhang, Xiaojing Wang, Fenghui Fan, Hong-Wei Wang, Jiawei Wang, Xueming Li and Sen-Fang Sui
10.1038/cr.2017.5
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Simultaneous enhancement of cellular and humoral immunity by the high salt formulation of Al(OH)3 adjuvant

Min Luo, Bin Shao, Jia-yun Yu, Ting Liu, Xiao Liang, Lian Lu, Ting-hong Ye, Zhi-yao He, Heng-yi Xiao and Xia-wei Wei
10.1038/cr.2017.14
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Single-cell exome sequencing identifies mutations in KCP, LOC440040, and LOC440563 as drivers in renal cell carcinoma stem cells

Chong Li, Song Wu, Zhao Yang, Xiaolong Zhang, Qi Zheng, Ling Lin, Zexiong Niu, Ruiqiang Li, Zhiming Cai and Lei Li
10.1038/cr.2016.150
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CORRIGENDUM

A positive role for polycomb in transcriptional regulation via H4K20me1

Xiangdong Lv, Zhijun Han, Hao Chen, Bo Yang, Xiaofeng Yang, Yuanxin Xia, Chenyu Pan, Lin Fu, Shuo Zhang, Hui Han, Min Wu, Zhaocai Zhou, Lei Zhang, Lin Li, Gang Wei and Yun Zhao
10.1038/cr.2017.50
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