RESEARCH HIGHLIGHTS

Love laughs at Locksmiths: Ubiquitylation of p62 unlocks its autophagy receptor potential

Owen Conway and Vladimir Kirkin
10.1038/cr.2017.56
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Cell fate conversion: a chromatin remodeling checkpoint revealed

Kenneth S Zaret
10.1038/cr.2017.44
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Moving towards totipotency without a single miR-acle

Noam Maoz and Yosef Buganim
10.1038/cr.2017.30
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Proteasomes on the chromosome

Michael Lichten
10.1038/cr.2017.28
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LncRNA-encoded peptides: More than translational noise?

Nathalie Rion and Markus A Rüegg
10.1038/cr.2017.35
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ORIGINAL ARTICLES

5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader

Xin Yang, Ying Yang, Bao-Fa Sun, Yu-Sheng Chen, Jia-Wei Xu, Wei-Yi Lai, Ang Li, Xing Wang, Devi Prasad Bhattarai, Wen Xiao, Hui-Ying Sun, Qin Zhu, Hai-Li Ma, Samir Adhikari2, Min Sun, Ya-Juan Hao, Bing Zhang, Chun-Min Huang, Niu Huang, Gui-Bin Jiang, Yong-Liang Zhao, Hai-Lin Wang, Ying-Pu Sun and Yun-Gui Yang
10.1038/cr.2017.55
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Extensive translation of circular RNAs driven by N6-methyladenosine

Yun Yang, Xiaojuan Fan, Miaowei Mao, Xiaowei Song, Ping Wu, Yang Zhang, Yongfeng Jin, Yi Yang, Lingling Chen, Yang Wang, Catherine CL Wong, Xinshu Xiao and Zefeng Wang
10.1038/cr.2017.31
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Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening

Shuyi Ji, Linying Zhu, Yimeng Gao, Xiaoran Zhang, Yupeng Yan1, Jin Cen, Rongxia Li, Rong Zeng, Lujian Liao, Chunhui Hou, Yawei Gao, Shaorong Gao, Gang Wei and Lijian Hui
10.1038/cr.2017.36
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Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress

Hong Peng, Jiao Yang, Guangyi Li, Qing You, Wen Han, Tianrang Li, Daming Gao, Xiaoduo Xie, Byung-Hoon Lee, Juan Du, Jian Hou, Tao Zhang, Hai Rao, Ying Huang, Qinrun Li, Rong Zeng, Lijian Hui, Hongyan Wang, Qin Xia, Xuemin Zhang, Yongning He, Masaaki Komatsu, Ivan Dikic, Daniel Finley and Ronggui Hu
10.1038/cr.2017.40
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Structure and mechanism of a group-I cobalt energy coupling factor transporter

Zhihao Bao, Xiaofeng Qi, Sen Hong, Ke Xu, Fangyuan He, Minhua Zhang, Jiugeng Chen, Daiyin Chao, Wei Zhao, Dianfan Li, Jiawei Wang and Peng Zhang
10.1038/cr.2017.38
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PKR activation and eIF2α phosphorylation mediate human globin mRNA splicing at spliceosome assembly

Lena Ilan, Farhat Osman, Lise Sarah Namer, Einav Eliahu, Smadar Cohen-Chalamish, Yitzhak Ben-Asouli, Yona Banai and Raymond Kaempfer
10.1038/cr.2017.39
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LETTERS TO THE EDITOR

Structural basis of stringent PAM recognition by CRISPR-C2c1 in complex with sgRNA

Dan Wu, Xiaoyu Guan, Yuwei Zhu, Kuan Ren and Zhiwei Huang
10.1038/cr.2017.46
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Reversible transition between hepatocytes and liver progenitors for in vitro hepatocyte expansion

Han Wu, Xu Zhou, Gong-Bo Fu, Zhi-Ying He, Hong-Ping Wu, Pu You, Charles Ashton, Xin Wang, Hong-Yang Wang and He-Xin Yan
10.1038/cr.2017.47
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Live cell single molecule-guided Bayesian localization super resolution microscopy

Fan Xu, Mingshu Zhang, Wenting He, Renmin Han, Fudong Xue, Zhiyong Liu, Fa Zhang, Jennifer Lippincott-Schwartz and Pingyong Xu
10.1038/cr.2015.160
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