RESEARCH HIGHLIGHTS

5-methylcytosine mediates nuclear export of mRNA

Dan Dominissini and Gideon Rechavi
10.1038/cr.2017.73
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Spontaneous DNA damage propels tumorigenicity

Ilio Vitale and Guido Kroemer
10.1038/cr.2017.43
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An evolving function of DNA-containing exosomes in chemotherapy-induced immune response

Paul Kurywchak1 and Raghu Kalluri1
10.1038/cr.2017.74
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Circular RNAs: Coding or noncoding?

Tim Schneider and Albrecht Bindereif
10.1038/cr.2017.70
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Seducing astrocytes to the dark side

Shuyi Ji, Linying Zhu, Yimeng Gao, Xiaoran Zhang, Yupeng Yan, Jin Cen, Rongxia Li, Rong Zeng, Lujian Liao, Chunhui Hou, Yawei Gao, Shaorong Gao, Gang Wei and Lijian Hui
10.1038/cr.2017.36
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Molecular assembly of rhodopsin with G protein-coupled receptor kinases

Yuanzheng He, Xiang Gao, Devrishi Goswami, Li Hou, Kuntal Pal, Yanting Yin, Gongpu Zhao, Oliver P Ernst, Patrick Griffin, Karsten Melcher and H Eric Xu
10.1038/cr.2017.72
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ORIGINAL ARTICLES

Fasting-induced hormonal regulation of lysosomal function

Liqun Chen, Ke Wang, Aijun Long, Liangjie Jia, Yuanyuan Zhang, Haiteng Deng, Yu Li, Jinbo Han and Yiguo Wang
10.1038/cr.2017.45
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Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells

Xinjian Liu, Fang Li, Qian Huang, Zhengxiang Zhang, Ling Zhou, Yu Deng, Min Zhou, Donald E Fleenor, He Wang, Michael B Kastan and Chuan-Yuan Li
10.1038/cr.2017.41
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Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation

Qiaoshi Lian, Jun Xu, Shanshan Yan, Min Huang, Honghua Ding, Xiaoyu Sun, Aiwei Bi, Jian Ding, Bing Sun and Meiyu Geng
10.1038/cr.2017.54
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Homology-mediated end joining-based targeted integration using CRISPR/Cas9

Xuan Yao, Xing Wang, Xinde Hu, Zhen Liu, Junlai Liu, Haibo Zhou, Xiaowen Shen, Yu Wei, Zijian Huang, Wenqin Ying, Yan Wang, Yan-Hong Nie, Chen-Chen Zhang, Sanlan Li, Leping Cheng, Qifang Wang, Yan Wu, Pengyu Huang, Qiang Sun1, Linyu Shi and Hui Yang
10.1038/cr.2017.76
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CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development

Lingbo Wang, Min-Yin Li, Chao Qu, Wan-Ying Miao, Qi Yin, Jiaoyang Liao, Hua-Teng Cao, Min Huang, Kai Wang, Erwei Zuo, Guangdun Peng, Shu-Xin Zhang, Guodong Chen, Qing Li, Ke Tang, Qian Yu8, Zhoujie Li, Catherine CL Wong, Guoliang Xu, Naihe Jing, Xiang Yu and Jinsong Li
10.1038/cr.2017.58
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LETTERS TO THE EDITOR

Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors

Jie Zhu, Chang Ming, Xin Fu, Yaou Duan, Duc Anh Hoang, Jeffrey Rutgard, Runze Zhang, Wenqiu Wang, Rui Hou, Daniel Zhang, Edward Zhang, Charlotte Zhang, Xiaoke Hao, Wenjun Xiong and Kang Zhang
10.1038/cr.2017.57
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Mitochondrial replacement by pre-pronuclear transfer in human embryos

Keliang Wu, Tailai Chen, Sexin Huang, Cuiqing Zhong, Junhao Yan, Xiaoyu Zhang, Jinsong Li, Yuan Gao, Han Zhao and Zi-Jiang Chen
10.1038/cr.2017.48
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ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds

Ruifeng Yao, Fei Wang, Zhenhua Ming, Xiaoxi Du, Li Chen, Yupei Wang, Wenhao Zhang, Haiteng Deng and Daoxin Xie
10.1038/cr.2017.3
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CORRIGENDUM

A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations

Xiaoping Han, Hao Yu, Daosheng Huang, Yang Xu, Assieh Saadatpour, Xia Li, Lengmei Wang, Jie Yu, Luca Pinello, Shujing Lai, Mengmeng Jiang, Xueying Tian, Fen Zhang, Yanhong Cen, Yuko Fujiwara, Wei Zhu, Bin Zhou, Tianhua Zhou, Hongwei Ouyang, Jianan Wang, Guo-Cheng Yuan, Shumin Duan, Stuart H Orkin and Guoji Guo
10.1038/cr.2017.77
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ERRATUM

A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations

Xiaoping Han, Hao Yu, Daosheng Huang, Yang Xu, Assieh Saadatpour, Xia Li, Lengmei Wang, Jie Yu, Luca Pinello, Shujing Lai, Mengmeng Jiang, Xueying Tian, Fen Zhang, Yanhong Cen, Yuko Fujiwara, Wei Zhu, Bin Zhou, Tianhua Zhou, Hongwei Ouyang, Jianan Wang, Guo-Cheng Yuan, Shumin Duan, Stuart H Orkin and Guoji Guo
10.1038/cr.2017.78
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