RESEARCH HIGHLIGHTS

Plant G-protein activation: connecting to plant receptor kinases

Kyle W. Bender and Cyril Zipfel
https://doi.org/10.1038/s41422-018-0046-2
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Ribophagy: new receptor discovered

Donna Denton and Sharad Kumar
https://doi.org/10.1038/s41422-018-0054-2
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ORIGINAL ARTICLES

The BH3-only protein BAD mediates TNFα cytotoxicitydespite concurrent activation of IKK and NF-κB in septicshock

Jie Yan , Hao Zhang, Jialing Xiang , Yu Zhao, Xiang Yuan, Beicheng Sun and Anning Lin
https://doi.org/10.1038/s41422-018-0041-7
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MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models

Zheng Xue , Daniel J. Vis , Alejandra Bruna , Tonci Sustic , Sake van Wageningen , Ankita Sati Batra , Oscar M. Rueda ,Evert Bosdriesz , Carlos Caldas , Lodewyk F. A. Wessels and René Bernards
https://doi.org/10.1038/s41422-018-0044-4
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Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis

Xiaoying Fan, Ji Dong , Suijuan Zhong , Yuan Wei , Qian Wu , Liying Yan, Jun Yong , Le Sun , Xiaoye Wang ,Yangyu Zhao , Wei Wang , Jie Yan , Xiaoqun Wang , Jie Qiaoand Fuchou Tang
https://doi.org/10.1038/s41422-018-0053-3
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Structure of the receptor-activated human TRPC6 and TRPC3 ion channels

Qinglin Tang 1, Wenjun Guo , Li Zheng , Jing-Xiang Wu , Meng Liu , Xindi Zhou, Xiaolin Zhang and Lei Chen
doi:10.1038/s41422-018-0038-2
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Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair

Zhiming Li , Yinglu Li , Ming Tang, Bin Peng , Xiaopeng Lu , Qiaoyan Yang, Qian Zhu, Tianyun Hou , Meiting Li, Chaohua Liu ,Lina Wang , Xingzhi Xu , Ying Zhao, Haiying Wang , Yang Yang and Wei-Guo Zhu
https://doi.org/10.1038/s41422-018-0048-0
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LETTERS TO THE EDITOR

The genomic landscape of small cell carcinoma of the esophagus

Feng Wang , Dong-Bing Liu , Qi Zhao, Gang Chen ,Xin-Ming Liu , Ying-Nan Wang , Hong Su , Yan-Ru Qin , Yi-Fu He, Qing-Feng Zou , Yan-Hui Liu , You-En Lin,Ze-Xian Liu , Jin-Xin Bei and Rui-Hua Xu
doi:10.1038/s41422-018-0039-1
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Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth

Yi Li , Huan Zhao , Xiuzhen Huang , Juan Tang ,Shaohua Zhang , Yan Li , Xiuxiu Liu , Lingjuan He ,Zhengyu Ju, Kathy O. Lui and Bin Zhou
https://doi.org/10.1038/s41422-
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PROTAC-induced BTK degradation as a novel therapy for mutated BTK C481S induced ibrutinib-resistant B-cell malignancies

Yonghui Sun , Xingwang Zhao , Ning Ding , Hongying Gao ,Yue Wu, Yiqing Yang, Meng Zhao, Jinseok Hwang ,Yuqin Song , Wanli Liu and Yu Rao
https://doi.org/10.1038/s41422-018-0055-1
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CORRIGENDA

Author Correction: IMMP2L: a mitochondrial protease suppressing cellular senescence

Valentina Sica and Guido Kroemer
https://doi.org/10.1038/s41422-018-0059-x
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