RESEARCH HIGHLIGHTS

IMMP2L: a mitochondrial protease suppressing cellular senescence

Valentina Sica and Guido Kroemer
https://doi.org/10.1038/s41422-018-0051-5
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Deadlier than the malate

Pingtao Ding, Hailong Guo1 and Jonathan D. G. Jones

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Aberrant erythropoiesis fuels tumor growth

Kyohei Nakamura and Mark J. Smyth
https://doi.org/10.1038/s41422-018-0047-1
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Dimethyl fumarate: targeting glycolysis to treat MS

Stefano Angiari and Luke A. O’Neill
https://doi.org/10.1038/s41422-018-0045-3
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REVIEWS

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

Ying Yang , Phillip J. Hsu , Yu-Sheng Chen and Yun-Gui Yang
https://doi.org/10.1038/s41422-018-0040-8
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ORIGINAL ARTICLES

Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death

Lifeng Yuan , Linhui Zhai , Lili Qian , De Huang , Yi Ding , Handan Xiang , Xiaojing Liu , J. Will Thompson , Juan Liu , Yong-Han He , Xiao-Qiong Chen , Jing Hu , Qing-Peng Kong , Minjia Tan 3 and Xiao-Fan Wang
https://doi.org/10.1038/s41422-018-0043-5
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Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate

Biao Qiu, Bingqing Xia , Qingtong Zhou , Yan Lu , Miaomiao He , Kazuya Hasegawa , Zhiqiang Ma , Fengyu Zhang ,Lichuan Gu, Qionglei Mao , Feng Wang , Suwen Zhao , Zhaobing Gao and Jun Liao
https://doi.org/10.1038/s41422-018-0032-8
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Phosphorylation of glutaminase by PKCε is essential for its enzymatic activity and critically contributes to tumorigenesis

Tianyu Han , Weihua Zhan , Mingxi Gan, Fanrong Liu , Bentong Yu , Y. Eugene Chin and Jian-Bin Wang
10.1038/s41422-018-0021-y
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SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation

Fang Yu , Guang Shi , Shimeng Cheng, Jiwei Chen , Shwu-Yuan Wu , Zhiqiang Wang, Nansong Xia, Yunhao Zhai,Zhenxing Wang, Yu Peng, Dong Wang, James X. Du, Lujian Liao, Sheng-Zhong Duan, Tieliu Shi, Jinke Cheng,Cheng-Ming Chiang, Jiwen Li and Jiemin Wong
10.1038/s41422-018-0023-9
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LETTERS TO THE EDITOR

Chemical-induced cardiac reprogramming in vivo

Chenwen Huang , Wanzhi Tu , Yanbin Fu , Jinxi Wang and Xin Xie
10.1038/s41422-018-0036-4
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A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma

Cun Wang, Haojie Jin2, Dongmei Gao, Liqin Wang , Bastiaan Evers , Zheng Xue , Guangzhi Jin , Cor Lieftink ,Roderick L. Beijersbergen , Wenxin Qin and René Bernards
10.1038/s41422-018-0020-z
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Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer

Shuangyan Tan , Qiheng Gou, Wenchen Pu, Chenglin Guo ,Yun Yang , Ke Wu , Yaxin Liu , Lunxu Liu, Yu-Quan Wei and Yong Peng
10.1038/s41422-018-0033-7
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