Cell Research

Volume 28 Issue 8, Aug 2018

The cartoon image shows that PTEN-L acts as a protein phosphatase (boat anchor) against phosphorylated ubiquitin (sail) to protect mitochondria (boat) from destruction by lysosome (reef). See page 787-802 by Liming Wang et al. for details.

RESEARCH HIGHLIGHTS

GPCR signaling: conformational activation of arrestins

Alem W. Kahsai1, Biswaranjan Pani and Robert J. Lefkowitz
https://doi.org/10.1038/s41422-018-0067-x
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Competing for enhancers: PVT1 fine-tunes MYC expression

Abhijit Parolia , Marcin Cieślik and Arul M. Chinnaiyan
https://doi.org/10.1038/s41422-018-0064-0
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ORIGINAL ARTICLES

PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy

Liming Wang, Yik-Lam Cho , Yancheng Tang, Jigang Wang, Jung-Eun Park, Yajun Wu , Chunxin Wang, Yan Tong , Ritu Chawla ,Jianbin Zhang , Yin Shi , Shuo Deng , Guang Lu , Yihua Wu , Hayden Weng-Siong Tan , Pornteera Pawijit , Grace Gui-Yin Lim ,Hui-Ying Chan , Jingzi Zhang , Lei Fang Hanry Yu , Yih-Cherng Liou , Mallilankaraman Karthik , Boon-Huat Bay ,Kah-Leong Lim1,10, Siu-Kwan Sze 3, Celestial T. Yap1 and Han-Ming Shen1,9
https://doi.org/10.1038/s41422-018-0056-0
Full Text | PDF | Abstract | Open Access

Tissue clearing of both hard and soft tissue organs with the PEGASOS method

Dian Jing , Shiwen Zhang , Wenjing Luo , Xiaofei Gao , Yi Men, Chi Ma 1, Xiaohua Liu , Yating Yi, Abhijit Bugde ,Bo O. Zhou, Zhihe Zhao , Quan Yuan , Jian Q. Feng , Liang Gao , Woo-Ping Ge and Hu Zhao
https://doi.org/10.1038/s41422-018-0049-z
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Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta

Yawei Liu, Xiaoying Fan , Rui Wang , Xiaoyin Lu , Yan-Li Dang , Huiying Wang , Hai-Yan Lin , Cheng Zhu , Hao Ge,James C. Cross and Hongmei Wang
https://doi.org/10.1038/s41422-018-0066-y
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DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling

Pengli Zheng, Qingzhou Chen, Xiaoyu Tian , Nannan Qian , Peiyuan Chai , Bing Liu, Junjie Hu , Craig Blackstone ,Desheng Zhu , Junlin Teng and Jianguo Chen
https://doi.org/10.1038/s41422-018-0065-z
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BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity

Wen Jiang , Songjie Feng, Shisheng Huang, Wenxia Yu , Guanglei Li , Guang Yang , Yajing Liu , Yu Zhang, Lei Zhang ,Yu Hou , Jia Chen , Jieping Chen and Xingxu Huang
https://doi.org/10.1038/s41422-018-0052-4
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LETTERS TO THE EDITOR

Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

Yi Yang , Chia-Wei Li , Li-Chuan Chan , Yongkun Wei, Jung-Mao Hsu , Weiya Xia , Jong-Ho Cha , Junwei Hou ,Jennifer L. Hsu, Linlin Sun and Mien-Chie Hung
https://doi.org/10.1038/s41422-018-0060-4
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Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion

Wei-Feng Cai, Cixiong Zhang, Yu-Qing Wu, Gui Zhuang,Zhiyun Ye , Chen-Song Zhangand Sheng-Cai Lin
https://doi.org/10.1038/s41422-018-0057-z
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Necroptosis of tumor cells leads to tumor necrosis and promotes tumor metastasis

Delong Jiao, Zhenyu Cai , Swati Choksi , Dan Ma ,Moran Choe , Hyung-Joon Kwon , Jin Young Baik , Brian G. Rowan , Chengyu Liu and Zheng-gang Liu
https://doi.org/10.1038/s41422-018-
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CORRIGENDA

Author Correction: Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth

Yi Li , Huan Zhao , Xiuzhen Huang , Juan Tang ,Shaohua Zhang , Yan Li , Xiuxiu Liu , Lingjuan He ,Zhengyu Ju, Kathy O. Lui and Bin Zhou
https://doi.org/10.1038/s41422-018-0063-1
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