EDITORIAL

Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses

Tuan M. Nguyen, Yang Zhangand Pier Paolo Pandolfi
https://doi.org/10.1038/s41422-020-0290-0
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RESEARCH HIGHLIGHTS

Meningeal lymphatics “drain” brain tumors

Mitsuhiro Kanamori and Jonathan Kipnis
https://doi.org/10.1038/s41422-020-0286-9
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First structural insights into CRISPR-Cas-guided DNA transposition

John van der Oost and Ioannis Mougiakos
https://doi.org/10.1038/s41422-020-0284-y
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Make or break: the ribosome as a regulator of mRNA decay

Anthony J. Veltri, Karole N. D’Orazio and Rachel Green
https://doi.org/10.1038/s41422-019-0271-3
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ORIGINAL ARTICLES

Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA

Min Zhang, Shumin Yang, Raman Nelakanti, Wentao Zhao, Gaochao Liu, Zheng Li, Xiaohui Liu, Tao Wu , Andrew Xiao and Haitao Li
https://doi.org/10.1038/s41422-019-0237-5
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m6A-dependent biogenesis of circular RNAs in male germ cells

Chong Tang, Yeming Xie, Tian Yu, Na Liu, Zhuqing Wang, Rebekah J. Woolsey, Yunge Tang, Xinzong Zhang,Weibing Qin , Ying Zhang, Ge Song, Weiwei Zheng, Juan Wang, Weitian Chen, Xiongyi Wei, Zhe Xie , Rachel Klukovich,Huili Zheng, David R. Quilici and Wei Yan
https://doi.org/10.1038/s41422-020-0279-8
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Meningeal lymphatic vessels regulate brain tumor drainage and immunity

Xueting Hu, Qiuping Deng, Lu Ma, Qingqing Li, Yidong Chen, Yuhan Liao, Fan Zhou, Chen Zhang, Linlin Shao, Jun Feng, Tubao He, Weihai Ning, Yan Kong, Yingqing Huo, Aibin He, Bing Liu, Jingjing Zhang, Ralf Adams, Yulong He, Fuchou Tang, Xiuwu Bian, Jincai Luo
https://doi.org/10.1038/s41422-020-0287-8
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In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids

Yan Yuan , Laihua Li, Qing Cheng, Feiyang Diao, Qiao Zeng, Xiaoyu Yang, Yibo Wu, Hao Zhang, Mingqian Huang,Junqing Chen, Quan Zhou, Yunfei Zhu, Rong Hua, Jianyu Tian, Xin Wang, Zuomin Zhou, Jie Hao, Jinjin Yu, Dong Hua,Jiayin Liu, Xuejiang Guo , Qi Zhouand Jiahao Sha
https://doi.org/10.1038/s41422-020-0283-z
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Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks

Yao Chen, Ruitu Lyu, Bowen Rong, Yuxuan Zheng , Zhen Lin,Ruofei Dai, Xi Zhang, Nannan Xie, Siqing Wang,Fuchou Tang , Fei Lanand Ming-Han Tong
https://doi.org/10.1038/s41422-020-0281-1
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LETTERS TO THE EDITOR

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Manli Wang, Ruiyuan Cao, Leike Zhang, Xinglou Yang, Jia Liu,Mingyue Xu, Zhengli Shi, Zhihong Hu , Wu Zhong and Gengfu Xiao
https://doi.org/10.1038/s41422-020-0282-0
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Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1

Li-Fei Tian, Yan-Ping Liu, Lianqi Chen , Qun Tang, Wei Wu, Wei Sun, Zhongzhou Chen and Xiao-Xue Yan

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Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies

Liren Wang, Linxi Li, Yanlin Ma , Handan Hu, Qi Li ,Yang Yang , Wenbang Liu, Shuming Yin, Wei Li, Bin Fu,Ryo Kurita, Yukio Nakamura, Mingyao Liu, Yongrong Lai and Dali Li
https://doi.org/10.1038/s41422-019-0267-z
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