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Table of Contents

Volume 33 Issue 9, Sep 2023

The image shows a Chinese idiom of “flying together”, wherein one bird represents “Cultured Embryo” and the other bird represents “E-assembloid”, and they carry the keys to together open the black box of human peri-implantation development. See page 661–678 by Zongyong Ai et al. for details.

EDITORIAL

Treating lung cancer: defining surgical curative time window

Fangqiu Fu, Zongwei Chen, Haiquan Chen
https://doi.org/10.1038/s41422-023-00852-w
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RESEARCH HIGHLIGHTS

Unveiling the hidden battlefield: dissecting the invasive zone in liver cancer

Valerie Chew
https://doi.org/10.1038/s41422-023-00855-7
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Lactylation regulates cardiac function

Shohini Ghosh-Choudhary, Toren Finkel
https://doi.org/10.1038/s41422-023-00857-5
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Atypical bacterial Argonautes regulate antiphage defense

Arpita Chakravarti, Dinshaw J. Patel
https://doi.org/10.1038/s41422-023-00862-8
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Sensing unsaturated fatty acids: insights from GPR120 signaling

Shicheng Zhang, Bryan L. Roth
https://doi.org/10.1038/s41422-023-00814-2
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Towards clinically meaningful expansion of human HSCs

Maria Florencia Tellechea, Jalila Chagraoui, Sandra Cohen, Guy Sauvageau
https://doi.org/10.1038/s41422-023-00817-z
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ORIGINAL ARTICLES

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

Zongyong Ai, Baohua Niu, Yu Yin, Lifeng Xiang, Gaohui Shi, Kui Duan, Sile Wang, Yingjie Hu, Chi Zhang, Chengting Zhang, Lujuan Rong, Ruize Kong, Tingwei Chen, Yixin Guo, Wanlu Liu, Nan Li, Shumei Zhao, Xiaoqing Zhu, Xuancheng Mai, Yonggang Li, Ze Wu, Yi Zheng, Jianping Fu, Weizhi Ji, Tianqing Li
https://doi.org/10.1038/s41422-023-00846-8
Full Text | PDF | Abstract | Open Access


α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure

Naijin Zhang, Ying Zhang, Jiaqi Xu, Pengbo Wang, Boquan Wu, Saien Lu, Xinxin Lu, Shilong You, Xinyue Huang, Mohan Li, Yuanming Zou, Mengke Liu, Yuanhui Zhao, Guozhe Sun, Wenbin Wang, Danxi Geng, Jingwei Liu, Liu Cao, Yingxian Sun
https://doi.org/10.1038/s41422-023-00844-w
Full Text | PDF | Abstract | Open Access


Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers

Xinwei Wang, Mu Wang, Tuo Xu, Ye Feng, Qiang Shao, Shuo Han, Xiaojing Chu, Yechun Xu, Shuling Lin, Qiang Zhao, Beili Wu
https://doi.org/10.1038/s41422-023-00830-2
Full Text | PDF | Abstract | Open Access


Lin28a maintains a subset of adult muscle stem cells in an embryonic-like state

Peng Wang, Xupeng Liu, Ziyue Yao, Yu Chen, Lanfang Luo, Kun Liang, Jun-Hao Elwin Tan, Min-Wen Jason Chua, Yan-Jiang Benjamin Chua, Shilin Ma, Liping Zhang, Wenwu Ma, Shuqing Liu, Wenhua Cao, Luyao Guo, Lu Guang, Yuefan Wang, He Zhao, Na Ai, Yun Li, Chunwei Li, Ruiqi Rachel Wang, Bin Tean Teh, Lan Jiang, Kang Yu, Ng Shyh-Chang
https://doi.org/10.1038/s41422-023-00818-y
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LETTERS TO THE EDITOR

Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2′-O-methylation

Li Chen, Li-Sheng Zhang, Chang Ye, Huiqing Zhou, Bei Liu, Boyang Gao, Zixin Deng, Changming Zhao, Chuan He, Bryan C. Dickinson
https://doi.org/10.1038/s41422-023-00836-w
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Cryo-EM structure of the ssDNA-activated SPARTA complex

Minghui Guo, Yuwei Zhu, Zhiying Lin, Dehui Yang, Anqi Zhang, Changyou Guo, Zhiwei Huang
https://doi.org/10.1038/s41422-023-00850-y
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