RESEARCH HIGHLIGHTS

FUSTer than stress granules: a prion-like domain warns plants of heat

Panagiotis N. Moschou, Peter V. Bozhkov
https://doi.org/10.1038/s41422-025-01133-4
Full Text | PDF | Abstract

Lysosomal EGFR functions as a GEF for Rheb

Tao Hou, Peiqiang Yan, Hiroyuki Inuzuka, Wenyi Wei
https://doi.org/10.1038/s41422-025-01126-3
Full Text | PDF | Abstract

Filament assembly powers NbaSPARDA in bacterial defense

Beibei Wang, Qiunan Jin, Hui Yang
https://doi.org/10.1038/s41422-025-01131-6
Full Text | PDF | Abstract

Grease, fuel and target — polyunsaturated lipids in metastasis

Annemarie Schwab, Thomas Brabletz
https://doi.org/10.1038/s41422-025-01089-5
Full Text | PDF | Abstract

NO-immune privilege for hematopoietic stem cells

Agathe L. Chédeville, Simón Méndez-Ferrer
https://doi.org/10.1038/s41422-025-01087-7
Full Text | PDF | Abstract

ORIGINAL ARTICLES

A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis

Pan Geng, Changxuan Li, Xuebo Quan, Jiaxuan Peng, Zhiying Yao, Yunhe Wang, Ming Yang, Yanning Wang, Yunfan Jin, Yan Xiong, Hongtao Liu, Yijun Qi, Peiguo Yang, Kai Huang, Xiaofeng Fang
https://doi.org/10.1038/s41422-025-01125-4
Full Text | PDF | Abstract | Open Access

Lysosomal EGFR acts as a Rheb-GEF independent of its kinase activity to activate mTORC1

Xiaobo He, Qiu-Xia Wang, Denghui Wei, Yujie Lin, Xia Zhang, Yuanzhong Wu, Xuexia Qian, Zhihao Lin, Beibei Xiao, Qinxue Wu, Zhen Wang, Fengtao Zhou, Zhihao Wei, Jingxuan Wang, Run Gong, Ruhua Zhang, Qingling Zhang, Ke Ding, Song Gao, Tiebang Kang
https://doi.org/10.1038/s41422-025-01110-x
Full Text | PDF | Abstract | Open Access

Target DNA-induced filament formation and nuclease activation of SPARDA complex

Feng Wang, Haijiang Xu, Chendi Zhang, Jialin Xue, Zhuang Li
https://doi.org/10.1038/s41422-025-01100-z
Full Text | PDF | Abstract | Open Access

LETTERS TO THE EDITOR

Pyrimidine synthase CAD deamidates and inactivates p53

Yue Qi, Zizheng Tan, Hanyu Chen, Ziqi Xiao, Liang Zhang, Boxuan Wu, Chennan Liu, Yunqian Gao, Xueyan Yang, Lingqian Wu, Lei Lu, Hongyan Wang
https://doi.org/10.1038/s41422-025-01112-9
Full Text | PDF | Abstract | Open Access

Mucin-like protein of Crimean-Congo hemorrhagic fever virus is a key virulence factor and a potent target for developing novel attenuated vaccine

Liushuai Li, Yajie Liu, Juhong Rao, Hengrui Hu, Jia Liu, Xi Wang, Jiang Li, Zhihong Hu, Manli Wang
https://doi.org/10.1038/s41422-025-01130-7
Full Text | PDF | Abstract

CORRIGENDA

Author Correction: A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis

Pan Geng, Changxuan Li, Xuebo Quan, Jiaxuan Peng, Zhiying Yao, Yunhe Wang, Ming Yang, Yanning Wang, Yunfan Jin, Yan Xiong, Hongtao Liu, Yijun Qi, Peiguo Yang, Kai Huang, Xiaofeng Fang
https://doi.org/10.1038/s41422-025-01134-3
Full Text | PDF | Abstract | Open Access

Author Correction: Raptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity

Ling-Qi Xie, Biao Hu, Ren-Bin Lu, Ya-Lun Cheng, Xin Chen, Jie Wen, Yao Xiao, Yu-Ze An, Ning Peng, Yu Dai, Genqing Xie, Qi Guo, Hui Peng, Xiang-Hang Luo
https://doi.org/10.1038/s41422-025-01123-6
Full Text | PDF | Abstract

Author Correction: Structural and functional evidence that GPR30 is not a direct estrogen receptor

Heng Liu, Shimeng Guo, Antao Dai, Peiyu Xu, Xin Li, Sijie Huang, Xinheng He, Kai Wu, Xinyue Zhang, Dehua Yang, Xin Xie, H. Eric Xu
https://doi.org/10.1038/s41422-025-01113-8
Full Text | PDF | Abstract