RESEARCH HIGHLIGHTS

The CXXC-TET bridge — mind the methylation gap!

Donncha S Dunican, Sari Pennings and Richard R Meehan
10.1038/cr.2013.71
Full Text | PDF | Abstract

Differentiation therapy for IDH1/2 mutant malignancies

Francine E Garrett-Bakelman and Ari M Melnick
10.1038/cr.2013.73
Full Text | PDF | Abstract

Regeneration potential of adult cardiac myocytes

Kyohei Oyama, Danny El-Nachef and W Robb MacLellan
10.1038/cr.2013.78
Full Text | PDF | Abstract

RhoGTPases — NODes for effector-triggered immunity in animals

Lynda M Stuart, and Laurent Boyer
10.1038/cr.2013.68
Full Text | PDF | Abstract

Ras and macropinocytosis: trick and treat

Fried J T Zwartkruis and Boudewijn M T Burgering
10.1038/cr.2013.79
Full Text | PDF | Abstract

ROS sets the stage for macrophage differentiation

Anthony Covarrubias, Vanessa Byles and Tiffany Horng
10.1038/cr.2013.88
Full Text | PDF | Abstract

ORIGINAL ARTICLES

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4 

Nianshuang Wang, Xuanling Shi, Liwei Jiang, Senyan Zhang, Dongli Wang, Pei Tong, Dongxing Guo, Lili Fu, Ye Cui, Xi Liu, Kelly C Arledge, Ying-Hua Chen, Linqi Zhang and Xinquan Wang
10.1038/cr.2013.92
Full Text | PDF | Abstract

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

Jianfeng Wu, Zhe Huang, Junming Ren, Zhirong Zhang, Peng He, Yangxin Li, Jianhui Ma, Wanze Chen, Yingying Zhang, Xiaojuan Zhou, Zhentao Yang, Su-Qin Wu, Lanfen Chen and Jiahuai Han
10.1038/cr.2013.91
Full Text | PDF | Abstract

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene 

Guang-Jing Hu, Jia Chen, Xiao-Nan Zhao, Jia-Jia Xu, Dong-Qing Guo, Ming Lu, Ming Zhu, Ying Xiong, Qin Li, Catherine CY Chang, Bao-Liang Song, Ta-Yuan Chang and Bo-Liang Li
10.1038/cr.2013.86
Full Text | PDF | Abstract

Viral degradasome hijacks mitochondria to suppress innate immunity

Ramansu Goswami, Tanmay Majumdar, Jayeeta Dhar, Saurabh Chattopadhyay, Sudip K Bandyopadhyay, Valentina Verbovetskaya, Ganes C Sen and Sailen Barik
10.1038/cr.2013.98
Full Text | PDF | Abstract

An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants

Minjie Cao, Xue LiuYan Zhang, Xiaoqian Xue, X Edward Zhou, Karsten Melcher, Pan Gao, Fuxing Wang, Liang Zeng, Yang Zhao, Yang Zhao, Pan Deng, Dafang Zhong, Jian-Kang Zhu, H Eric Xu and Yong Xu
10.1038/cr.2013.95
Full Text | PDF | Abstract

LETTERS TO THE EDITOR

Crystal structure and nucleotide selectivity of human IFIT5/ISG58

Feng Feng, Lingmin Yuan, Yao E Wang, Christopher Crowley3, Zongyang Lv, Jingjing Li, Yingfang Liu, Genhong Cheng, Su Zeng and Huanhuan Liang
10.1038/cr.2013.80
Full Text | PDF | Abstract

Generation of RAG 1- and 2-deficient rabbits by embryo microinjection of TALENs

Jun Song, Juan Zhong, Xiaogang Guo, Yongqiang Chen, Qingjian Zou1,3, Jiao Huang, Xiaoping Li, Quanjun Zhang, Zhiwu Jiang, Chengcheng Tang, Huaqiang Yang, Tao Liu, Peng Li, Duanqing Pei and Liangxue Lai
10.1038/cr.2013.85
Full Text | PDF | Abstract