RESEARCH HIGHLIGHTS

Producing GM-CSF: a unique T helper subset?

Dietmar Herndler-Brandstetter and Richard A Flavell
10.1038/cr.2014.155
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An ingredient for the elixir of youth

Rebecca E Andersen and Daniel A Lim
10.1038/cr.2014.107
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Mixed messages: Re-initiation factors regulate translation of animal mRNAs

Benedikt Obermayer and Nikolaus Rajewsky
10.1038/cr.2014.114
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Backseat drivers: Cargo adaptors and dynactin activate cytoplasmic dynein motility

Mark P Dodding
10.1038/cr.2014.115
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Backseat drivers: Regulation of dynein motility

Mark P Dodding
10.1038/cr.2014.115
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ORIGINAL ARTICLES

STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation

Wanqiang Sheng, Fan Yang, Yi Zhou, Henry Yang, Pey Yng Low, David Michael Kemeny, Patrick Tan, Akira Moh, Mark H Kaplan, Yongliang Zhang and Xin-Yuan Fu
10.1038/cr.2014.154
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FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis

Xu Zhao, Ying Yang, Bao-Fa Sun, Yue Shi, Xin Yang, Wen Xiao, Ya-Juan Hao, Xiao-Li Ping, Yu-Sheng Chen, Wen-Jia Wang, Kang-Xuan Jin, Xing Wang, Chun-Min Huang, Yu Fu, Xiao-Meng Ge, Shu-Hui Song, Hyun Seok Jeong, Hiroyuki Yanagisawa, Yamei Niu, Gui-Fang Jia, Wei Wu, Wei-Min Tong, Akimitsu Okamoto, Chuan He, Jannie M Rendtlew Danielsen, Xiu-Jie Wang and Yun-Gui Yang
10.1038/cr.2014.151N6-methyladenosine (m6A); METTL3; FTO; mRNA splicing; adipogenesis
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N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment

Boon-Seng Soh, Kristina Buac, Huansheng Xu, Edward Li, Shi-Yan Ng, Hao Wu, Jolanta Chmielowiec, Xin Jiang, Lei Bu, Ronald A Li, Chad Cowan and Kenneth R Chien
10.1038/cr.2014.142
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SUVR2 is involved in transcriptional gene silencing by associating with SNF2-related chromatin-remodeling proteins in Arabidopsis

Yong-Feng Han, Kun Dou, Ze-Yang Ma, Su-Wei Zhang, Huan-Wei Huang, Lin Li, Tao Cai, She Chen, Jian-Kang Zhu and Xin-Jian He
10.1038/cr.2014.156
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Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction

Mei Hua Jiang, Bing Cai, Ying Tuo, Jiancheng Wang, Zhi Jun Zang, Xiang'an Tu, Yong Gao, Zhijian Su, Weiqiang Li, Guilan Li, Min Zhang, Jianwei Jiao, Zi Wan, Chunhua Deng, Bruce T Lahn and Andy Peng Xiang
10.1038/cr.2014.149
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LETTERS TO THE EDITOR

Crystal structure of a bacterial homologue of SWEET transporters

Jing Wang, Chuangye Yan, Yini Li, Kunio Hirata, Masaki Yamamoto, Nieng Yan and Qi Hu
10.1038/cr.2014.144
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Structure of the YTH domain of human YTHDF2 in complex with an m⁶A mononucleotide reveals an aromatic cage for m⁶A recognition

Fudong Li, Debiao Zhao, Jihui Wu and Yunyu Shi
10.1038/cr.2014.153
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Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine

Tingting Zhu, Ian A Roundtree, Ping Wang1, Xiao Wang, Li Wang, Chang Sun, Yuan Tian, Jie Li, Chuan He and Yanhui Xu
10.1038/cr.2014.152
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