EDITORIAL

Recent progress in ubiquitin and ubiquitin-like protein (Ubl) signaling

Ronggui Hu and Mark Hochstrasser
10.1038/cr.2016.43
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RESEARCH HIGHLIGHTS

Mex3B, a coreceptor to present dsRNA to TLR3

Shu Zhu, Geng Wang, Xuqiu Lei and Richard A Flavell
10.1038/cr.2016.29
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Depending on maternal Yap

Eszter Posfai and Janet Rossant
10.1038/cr.2016.37
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tRNA fragments: novel players in intergenerational inheritance

Katharina Gapp and Eric A Miska
10.1038/cr.2016.24
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Keeping homologous recombination in check

Kasper Fugger and Stephen C West
10.1038/cr.2016.25
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REVIEWS

Ubiquitin modifications

Kirby N Swatek and David Komander
10.1038/cr.2016.39
Full Text | PDF | Abstract | Open Access

E2 enzymes: more than just middle men

Mikaela D Stewart, Tobias Ritterhoff, Rachel E Klevit and Peter S Brzovic
10.1038/cr.2016.35
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Substrate specificity of the ubiquitin and Ubl proteases

Judith A Ronau, John F Beckmann and Mark Hochstrasser
10.1038/cr.2016.38
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Ubiquitin signaling in immune responses

Hongbo Hu and Shao-Cong Sun
10.1038/cr.2016.40
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Drugging the undruggables: exploring the ubiquitin system for drug development

Xiaodong Huang and Vishva M Dixit
10.1038/cr.2016.31
Full Text | PDF | Abstract | Open Access

Bacteria-host relationship: ubiquitin ligases as weapons of invasion

Timurs Maculins, Evgenij Fiskin, Sagar Bhogaraju and Ivan Dikic
10.1038/cr.2016.30
Full Text | PDF | Abstract | Open Access