Cell Research

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Volume 27 Issue 8, Aug 2017

RESEARCH HIGHLIGHTS

Cardiomyocyte proliferation: remove brakes and push accelerators

Lingjuan He and Bin Zhou
10.1038/cr.2017.91
Full Text | PDF | Abstract

Reassembling embryos in vitro from component stem cells

Caroline Kubaczka and George Q Daley
10.1038/cr.2017.61
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Repolarizing macrophages improves breast cancer therapy

Luca Cassetta1 and Jeffrey W Pollard
10.1038/cr.2017.63
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It takes two to transport via an elevator

Bernadette Byrne
10.1038/cr.2017.89
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ORIGINAL ARTICLES

Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells

Fan Guo, Lin Li, Jingyun Li, Xinglong Wu, Boqiang Hu, Ping Zhu, Lu Wen and Fuchou Tang
10.1038/cr.2017.82
Full Text | PDF | Abstract | Open Access

Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2

Meisheng Ma, Jun-Jie Liu, Yan Li, Yuwei Huang, Na Ta, Yang Chen, Hua Fu, Ming-Da Ye, Yuehe Ding, Weijiao Huang, Jia Wang, Meng-Qiu Dong, Li Yu and Hong-Wei Wang
10.1038/cr.2017.94
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Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair

Ajit Magadum, Yishu Ding, Lan He, Teayoun Kim, Mohankrishna Dalvoy Vasudevarao, Qinqiang Long, Kevin Yang, Nadeera Wickramasinghe, Harsha V Renikunta, Nicole Dubois, Gilbert Weidinger, Qinglin Yang and Felix B Engel
10.1038/cr.2017.84
Full Text | PDF | Abstract | Open Access

Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters

Xinzhe Yu, Guanghui Yang, Chuangye Yan, Javier L Baylon, Jing Jiang, He Fan, Guifeng Lu, Kazuya Hasegawa, Hideo Okumura, Tingliang Wang, Emad Tajkhorshid, Shuo Li and Nieng Yan
10.1038/cr.2017.83
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Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

Young-hee Lee, Natalia Martin-Orozco, Peilin Zheng, Jing Li, Peng Zhang, Haidong Tan, Hyun Jung Park, Mira Jeong, Seon Hee Chang, Byung-Seok Kim, Wei Xiong, Wenjuan Zang, Li Guo, Yang Liu, Zhong-jun Dong, Willem W Overwijk, Patrick Hwu, Qing Yi, Larry Kwak, Zhiying Yang, Tak W Mak, Wei Li, Laszlo G Radvanyi, Ling Ni, Dongfang Liu and Chen Dong
10.1038/cr.2017.90
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Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction

Zhong Li, Matthew Brecher, Yong-Qiang Deng, Jing Zhang, Srilatha Sakamuru, Binbin Liu, Ruili Huang, Cheri A Koetzner, Christina A Allen, Susan A Jones, Haiying Chen, Na-Na Zhang, Min Tian2, Fengshan Gao, Qishan Lin, Nilesh Banavali, Jia Zhou, Nathan Boles, Menghang Xia, Laura D Kramer, Cheng-Feng Qin and Hongmin Li
10.1038/cr.2017.88
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LETTERS TO THE EDITOR

Clonal analysis reveals remarkable functional heterogeneity during hematopoietic stem cell emergence

Hui Ye, Xiaobo Wang, Zongcheng Li, Fan Zhou, Xianlong Li, Yanli Ni, Weijing Zhang, Fuchou Tang, Bing Liu and Yu Lan
10.1038/cr.2017.64
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Polar bodies are efficient donors for reconstruction of human embryos for potential mitochondrial replacement therapy

Keliang Wu, Cuiqing Zhong, Tailai Chen, Xiaoyu Zhang, Wenrong Tao, Jingye Zhang, Hongchang Li, Han Zhao, Jinsong Li and Zi-Jiang Chen
10.1038/cr.2017.67
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CORRIGENDUM

YAP activates the Hippo pathway in a negative feedback loop

Xiaoming Dai, Huan Liu, Shuying Shen, Xiaocan Guo, Huan Yan, Xinyan Ji, Li Li, Jun Huang, Xin-Hua Feng and Bin Zhao
10.1038/cr.2017.96
Full Text | PDF | Abstract