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Table of Contents

Volume 28 Issue 10, Oct 2018


RNA-binding protein ROD1/PTBP3 functions as a “compass” to guide AID targeting via bidirectionally transcribed RNAs (red ball represents hotspot regions). Cover artwork is contributed by Lantao Gou. See page 981-995 by Juan Chen et al. for details.

RESEARCH HIGHLIGHTS

Guiding a mutator in antibody diversification

Ming Tian and Frederick W. Alt
https://doi.org/10.1038/s41422-018-0085-8
Full Text | PDF | Abstract


Staged profiling of sperm development in sync

Navin B. Ramakrishna and M. Azim Surani
https://doi.org/10.1038/s41422-018-0088-5
Full Text | PDF | Abstract


cGAS activation in phased droplets

Yongbo Liu , Hua-Bing Li and Richard A. Flavell
https://doi.org/10.1038/s41422-018-0087-6
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REVIEWS

Skeletal muscle mitochondrial remodeling in exercise and diseases

Zhenji Gan , Tingting Fu , Daniel P. Kelly and Rick B. Vega
https://doi.org/10.1038/s41422-018-0078-7
Full Text | PDF | Abstract


ORIGINAL ARTICLES

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes

Juan Chen , Zhaokui Cai , Meizhu Bai , Xiaohua Yu , Chao Zhang , Changchang Cao , Xihao Hu , Lei Wang , Ruibao Su ,Di Wang , Lei Wang , Yingpeng Yao , Rong Ye , Baidong Hou , Yang Yu1, Shuyang Yu7, Jinsong Li3,4 and Yuanchao Xue1,2
https://doi.org/10.1038/s41422-018-0076-9
Full Text | PDF | Abstract | Open Access


STAT3 associates with vacuolar H+-ATPase and regulates cytosolic and lysosomal pH

Bin Liu , Johan Palmfeldt , Lin Lin , Alexandria Colaço , Knut K. B. Clemmensen , Jinrong Huang , Fengping Xu , Xin Liu , Kenji Maeda , Yonglun Luo and Marja Jäättelä
https://doi.org/10.1038/s41422-018-0080-0
Full Text | PDF | Abstract | Open Access


A post-ingestive amino acid sensor promotes food consumption in Drosophila

Zhe Yang , Rui Huang , Xin Fu, Gaohang Wang, Wei Qi , Decai Mao, Zhaomei Shi , Wei L. Shenand Liming Wang
https://doi.org/10.1038/s41422-018-0084-9
Full Text | PDF | Abstract | Open Access


Structure of the intact 14-subunit human cytochrome c oxidase

Shuai Zong , Meng Wu, Jinke Gu, Tianya Liu, Runyu Guo and Maojun Yang
https://doi.org/10.1038/s41422-018-0071-1
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LETTERS TO THE EDITOR

Loss of YTHDF2-mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration

Hu Wang , Hongna Zuo, Jin Liu , Fei Wen , Yawei Gao ,Xudong Zhu, Bo Liu, Feng Xiao , Wengong Wang ,Gang Huang , Bin Shen and Zhenyu Ju
https://doi.org/10.1038/s41422-018-0082-y
Full Text | PDF | Abstract


Threshold for neural tube defect risk by accumulated singleton loss-of-function variants

Zhongzhong Chen , Yunping Lei , Yufang Zheng,Vanessa Aguiar-Pulido , M. Elizabeth Ross , Rui Peng , Li Jin ,Ting Zhang, Richard H. Finnell and Hongyan Wang
https://doi.org/10.1038/s41422-018-0061-3
Full Text | PDF | Abstract | Open Access