RESEARCH HIGHLIGHTS

m6A reader suppression bolsters HSC expansion

Xinxin Huang and Hal E. Broxmeyer
https://doi.org/10.1038/s41422-018-0081-z
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p53 REEPs to sow ER–mitochondrial contacts

Florian J. Bock and Stephen W. G. Tait
https://doi.org/10.1038/s41422-018-0073-z
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ORIGINAL ARTICLES

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

Yao Chen 1, Yuxuan Zheng 2,3,4, Yun Gao 2,3,4, Zhen Lin 1, Suming Yang1, Tongtong Wang 1, Qiu Wang 1, Nannan Xie 1, Rong Hua 5,Mingxi Liu 5, Jiahao Sha 5, Michael D. Griswold 6, Jinsong Li 1, Fuchou Tang 2,3,4 and Ming-Han Tong 1
https://doi.org/10.1038/s41422-018-0074-y
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Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy

Yaowang Li , Chunyu Zhao , Feng Luo , Zhenying Liu , Xinrui Gui , Zhipu Luo , Xiang Zhang , Dan Li , Cong Liu and Xueming Li
https://doi.org/10.1038/s41422-018-0075-x
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Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion

Zhenrui Li , Pengxu Qian , Wanqing Shao, Hailing Shi , Xi C. He, Madelaine Gogol, Zulin Yu, Yongfu Wang , Meijie Qi, Yunfei Zhu , John M. Perry, Kai Zhang , Fang Tao, Kun Zhou , Deqing Hu , Yingli Han , Chongbei Zhao, Richard Alexander ,Hanzhang Xu , Shiyuan Chen , Allison Peak, Kathyrn Hall, Michael Peterson , Anoja Perera, Jeffrey S. Haug, Tari Parmely,Hua Li , Bin Shen , Julia Zeitlinger, Chuan He and Linheng Li
https://doi.org/10.1038/s41422-018-0072-0
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Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors

Dawei Liu , Xiaoxing Kou , Chider Chen , Shiyu Liu, Yao Liu, Wenjing Yu, Tingting Yu , Ruili Yang , Runci Wang ,Yanheng Zhou and Songtao Shi
https://doi.org/10.1038/s41422-018-0070-2
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Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis

Lin He , Xinhua Liu , Jianguo Yang , Wanjin Li , Shumeng Liu , Xujun Liu , Ziran Yang, Jie Ren , Yue Wang , Lin Shan ,Chengjian Guan, Fei Pei , Liandi Lei, Yu Zhang , Xia Yi, Xiaohan Yang , Jing Liang , Rong Liu , Luyang Sun and Yongfeng Shang
https://doi.org/10.1038/s41422-018-0079-6
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LETTERS TO THE EDITOR

Mettl3–Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells

Qi Jason Yao , Lina Sang , Minghui Lin , Xiujuan Yin ,Wenjie Dong , Yuping Gong and Bo O. Zhou
https://doi.org/10.1038/s41422-018-0062-2
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m6A RNA modification controls autophagy through upregulating ULK1 protein abundance

Shouheng Jin, Xiya Zhang , Yanyan Miao, Puping Liang ,Kaiyu Zhu , Yuanchu She , Yaoxing Wu, Di-Ao Liu , Junjiu Huang,Jian Ren and Jun Cui
https://doi.org/10.1038/s41422-018-
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Cryo-EM structure of the human α5β3 GABAA receptor

Si Liu , Lingyi Xu , Fenghui Guan , Yun-Tao Liu , Yanxiang Cui,Qing Zhang , Xiang Zheng , Guo-Qiang Bi , Z. Hong Zhou , Xiaokang Zhang and Sheng Ye
https://doi.org/10.1038/s41422-018-0077-8
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