RESEARCH HIGHLIGHTS

Keeping innate immune response in check: when cGAS meets the nucleosome

Wei Xie, Dinshaw J. Patel
https://doi.org/10.1038/s41422-020-00423-3
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Resident macrophages keep mitochondria running in the heart

Ronald J. Vagnozzi, Jeffery D. Molkentin
https://doi.org/10.1038/s41422-020-00427-z
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The SARS-CoV-2 spike protein: balancing stability and infectivity

Imre Berger, Christiane Schaffitzel
https://doi.org/10.1038/s41422-020-00430-4
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Ferroptosis: the Good, the Bad and the Ugly

Maceler Aldrovandi, Marcus Conrad
https://doi.org/10.1038/s41422-020-00434-0
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ORIGINAL ARTICLES

Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration

Shen’ao Zhou, Wei Zhang, Gaihong Cai, Yingzhe Ding, Caixia Wei, Sheng Li, Yu Yang, Jie Qin, Dan Liu, Hao Zhang, Xiexiang Shao, Jianhua Wang, Hongye Wang, Wenjun Yang, Huating Wang, She Chen, Ping Hu, Liming Sun
https://doi.org/10.1038/s41422-020-00393-6
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Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19

Yuying Liu, Jiadi Lv, Jiangning Liu, Man Li, Jing Xie, Qi Lv, Wei Deng, Nannan Zhou, Yabo Zhou, Jiangping Song, Peng Wang, Chuan Qin, Wei-Min Tong, Bo Huang
https://doi.org/10.1038/s41422-020-00435-z
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Structural basis for nucleosome-mediated inhibition of cGAS activity

Duanfang Cao, Xiaonan Han, Xiaoyi Fan, Rui-Ming Xu, Xinzheng Zhang
https://doi.org/10.1038/s41422-020-00422-4
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A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor

Wen Sun, Li-Nan Chen, Qingtong Zhou, Li-Hua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dan-Dan Shen, Fenghui Zhao, Fulai Zhou, Xiaoqing Cai, Yan Chen, Yan Zhou, Sarina Gadgaard, Wijnand J. C. van der Velden, Suwen Zhao, Yi Jiang, Mette M. Rosenkilde, H. Eric Xu, Yan Zhang, Ming-Wei Wang
https://doi.org/10.1038/s41422-020-00442-0
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Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level

Xin Wang, Li Yang, Yan-Chun Wang, Zi-Ran Xu, Ye Feng, Jing Zhang, Yi Wang, Cheng-Ran Xu
https://doi.org/10.1038/s41422-020-0378-6
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Structural mechanism of phospholipids translocation by MlaFEDB complex

Ximin Chi, Qiongxuan Fan, Yuanyuan Zhang, Ke Liang, Li Wan, Qiang Zhou, Yanyan Li
https://doi.org/10.1038/s41422-020-00404-6
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LETTERS TO THE EDITOR

Resolving individual atoms of protein complex by cryo-electron microscopy

Kaiming Zhang, Grigore D. Pintilie, Shanshan Li, Michael F. Schmid, Wah Chiu
https://doi.org/10.1038/s41422-020-00432-2
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Structural insights into the activation of GLP-1R by a small molecule agonist

Honglei Ma, Wei Huang, Xiaoxi Wang, Lihua Zhao, Yi Jiang, Feng Liu, Wei Guo, Xianqiang Sun, Wenge Zhong, Daopeng Yuan, H. Eric Xu
https://doi.org/10.1038/s41422-020-0384-8
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Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA

Hui Chen, Yang Cui, Xuling Han, Wei Hu, Min Sun, Yong Zhang, Pei-Hui Wang, Guangtao Song, Wei Chen, Jizhong Lou
https://doi.org/10.1038/s41422-020-00408-2
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