RESEARCH HIGHLIGHTS

Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1

Markus Hoffmann, Stefan Pöhlmann
https://doi.org/10.1038/s41422-021-00603-9
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UHRF1: a novel metabolic guardian restricting AMPK activity

Che-Chia Hsu, Yau-Sheng Tsai, Hui-Kuan Lin
https://doi.org/10.1038/s41422-021-00589-4
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Alluminating structure key to stress tolerance

Matthew Gilliham, Maria Hrmova
https://doi.org/10.1038/s41422-021-00604-8
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How did a novel X-linked gene become essential for male determination?

Scott William Roy
https://doi.org/10.1038/s41422-021-00577-8
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ORIGINAL ARTICLES

Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2

Shaojun Zhang, Wenze Huang, Lili Ren, Xiaohui Ju, Mingli Gong, Jian Rao, Lei Sun, Pan Li, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhang
https://doi.org/10.1038/s41422-021-00581-y
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Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2

Yunqing Gu, Jun Cao, Xinyu Zhang, Hai Gao, Yuyan Wang, Jia Wang, Juan He, Xiaoyi Jiang, Jinlan Zhang, Guanghui Shen, Jie Yang, Xichen Zheng, Gaowei Hu, Yuanfei Zhu, Shujuan Du, Yunkai Zhu, Rong Zhang, Jianqing Xu, Fei Lan, Di Qu, Guoliang Xu, Yun Zhao, Dong Gao, Youhua Xie, Min Luo, Zhigang Lu
https://doi.org/10.1038/s41422-021-00595-6
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Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics

Suwei Gao, Qiang Shi, Yifan Zhang, Guixian Liang, Zhixin Kang, Baofeng Huang, Dongyuan Ma, Lu Wang, Jianwei Jiao, Xiangdong Fang, Cheng-Ran Xu, Longqi Liu, Xun Xu, Berthold Göttgens, Cheng Li, Feng Liu
https://doi.org/10.1038/s41422-021-00540-7
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Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function

Xiang Xu, Guangjin Ding, Caizhi Liu, Yuhan Ding, Xiaoxin Chen, Xiaoli Huang, Chen-Song Zhang, Shanxin Lu, Yunpeng Zhang, Yuanyong Huang, Zhaosu Chen, Wei Wei, Lujian Liao, Shu-Hai Lin, Jingya Li, Wei Liu, Jiwen Li, Sheng-Cai Lin, Xinran Ma, Jiemin Wong
https://doi.org/10.1038/s41422-021-00565-y
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K_2P18.1 translates T cell receptor signals into thymic regulatory T cell development

Tobias Ruck, Stefanie Bock, Steffen Pfeuffer, Christina B. Schroeter1, Derya Cengiz, Paul Marciniak, Maren Lindner, Alexander Herrmann, Marie Liebmann, Stjepana Kovac, Lukas Gola, Leoni Rolfes, Marc Pawlitzki, Nils Opel, Tim Hahn, Udo Dannlowski, Thomas Pap, Felix Luessi, Julian A. Schreiber, Bernhard Wünsch, Tanja Kuhlmann, Guiscard Seebohm, Björn Tackenberg, Patricia Seja, Frank Döring, Erhard Wischmeyer, Achmet Imam Chasan, Johannes Roth, Luisa Klotz, Gerd Meyer zu Hörste, Heinz Wiendl, Tobias Marschall, Stefan Floess, Jochen Huehn, Thomas Budde, Tobias Bopp, Stefan Bittner, Sven G. Meuth
https://doi.org/10.1038/s41422-021-00580-z
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Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis

Jiangqin Wang, Xiafei Yu, Zhong Jie Ding, Xiaokang Zhang, Yanping Luo, Ximing Xu, Yuan Xie, Xiaoxiao Li, Tian Yuan, Shao Jian Zheng, Wei Yang, Jiangtao Guo
https://doi.org/10.1038/s41422-021-00587-6
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LETTERS TO THE EDITOR

SDX on the X chromosome is required for male sex determination

Junfeng Zhan, Peng Cui, Ziqi Yu, Wei Qu, Mengcheng Luo
https://doi.org/10.1038/s41422-021-00539-0
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Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern

Jingwen Ai, Haocheng Zhang, Qiran Zhang, Yi Zhang, Ke Lin, Zhangfan Fu, Jieyu Song, Yuanhan Zhao, Mingxiang Fan, Hongyu Wang, Chao Qiu, Yang Zhou, Wenhong Zhang
https://doi.org/10.1038/s41422-021-00590-x
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Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine

Yunlong Cao, Xiaohua Hao, Xi Wang, Qianhui Wu, Rui Song, Dong Zhao, Weiliang Song, Yao Wang, Ayijiang Yisimayi, Wei Wang, Juan Du, Hongjie Yu, Xiaoliang Sunney Xie, Ronghua Jin
https://doi.org/10.1038/s41422-021-00596-5
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