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Table of Contents

Volume 34 Issue 4, Apr 2024

The cover image illustrates the aluminum (Al) ion receptor ALR1 (Beacon Tower)that senses toxic aluminum ions, inducing reactive oxygen species (ROS; smoke) generation and accumulation of STOP1 (commander),thereby activating organic acid anion (arrow) secretion to detoxify Al. See page 281–294 by Zhong Jie Ding et al. for details.

RESEARCH HIGHLIGHTS

Sensing the toxic aluminum cations in acidic soils

Peter R. Ryan, Jianli Yang
https://doi.org/10.1038/s41422-024-00935-2
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CCHFV entry via LDLR keeps it ‘ticking’?

Ahmed K. Oraby, David J. Marchant
https://doi.org/10.1038/s41422-024-00928-1
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Enabling whole pathway reconstruction using artificial chromosomes

Zihe Liu, Jens Nielsen
https://doi.org/10.1038/s41422-024-00943-2
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A precision counterstrike on central nervous system autoimmunity

Aimee S. Payne, Sangwook Oh
https://doi.org/10.1038/s41422-023-00907-y
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Decoding Golgiphagy: selective recycling under stress

Alexis González, Ivan Dikić
https://doi.org/10.1038/s41422-023-00905-0
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Flooding plant apoplast through water and solute channels

Jianping Zhang, Daowen Wang, Zheng Qing Fu
https://doi.org/10.1038/s41422-023-00898-w
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ORIGINAL ARTICLES

The LRR receptor-like kinase ALR1 is a plant aluminum ion sensor

Zhong Jie Ding, Chen Xu, Jing Ying Yan, Yu Xuan Wang, Meng Qi Cui, Jun Jie Yuan, Ya Nan Wang, Gui Xin Li, Jian Xiang Wu, Yun Rong Wu, Ji Ming Xu, Chun Xiao Li, Yuan Zhi Shi, Chuan Zao Mao, Jiang Tao Guo, Jian Min Zhou, Moussa Benhamed, Nicholas P. Harberd, Shao Jian Zheng
https://doi.org/10.1038/s41422-023-00915-y
Full Text | PDF | Abstract | Open Access


B cell-reactive triad of B cells, follicular helper and regulatory T cells at homeostasis

Yihan Lin, Zurong Wan, Bo Liu, Jiacheng Yao, Tianqi Li, Fang Yang, Jianhua Sui, Yongshan Zhao, Wanli Liu, Xuyu Zhou, Jianbin Wang, Hai Qi
https://doi.org/10.1038/s41422-024-00929-0
Full Text | PDF | Abstract | Open Access


Convenient synthesis and delivery of a megabase-scale designer accessory chromosome empower biosynthetic capacity

Yuan Ma, Shuxin Su, Zongheng Fu, Chu Zhou, Bin Qiao, Yi Wu, Ying-Jin Yuan
https://doi.org/10.1038/s41422-024-00934-3
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LETTERS TO THE EDITOR

Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3

Fahui Li, Linhua Tai, Xiaoyu Sun, Zhenyu Lv, Wenqin Tang, Tianxin Wang, Ziyi Zhao, Daohong Gong, Shaohua Ma, Shichen Tang, Quanchang Gu, Xiaolei Zhu, Minling Yu, Xiaohong Liu, Jiangyun Wang
https://doi.org/10.1038/s41422-023-00914-z
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Base editing effectively prevents early-onset severe cardiomyopathy in Mybpc3 mutant mice

Shuo Wu, Ping Yang, Zilong Geng, Yige Li, Zhizhao Guo, Yingmei Lou, Shasha Zhang, Junhao Xiong, Huan Hu, Xiaoling Guo, William T. Pu, Yan Zhang, Dan Zhu, Bing Zhang
https://doi.org/10.1038/s41422-024-00930-7
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Editorial Expression of Concern

Editorial Expression of Concern: HDAC2 phosphorylationdependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs ofp21 in VSMCs

Bin Zheng, Mei Han, Ya-nan Shu, Ying-jie Li, Sui-bing Miao, Xin-hua Zhang, Hui-jing Shi, Tian Zhang, Jin-kun Wen
https://doi.org/10.1038/s41422-024-00947-y
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