RESEARCH HIGHLIGHTS

RNA-guided genome editing à la carte

Philippe Horvath and Rodolphe Barrangou
10.1038/cr.2013.39
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Viral counterattack against the host innate immune system

Bin Wu and Sun Hur
10.1038/cr.2013.32
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Unwinding the Wnt action of Casein Kinase1

Daniel GR Yim and David M Virshup
10.1038/cr.2013.51
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Engaging the p53 metabolic brake drives senescence

Dadi Jiang and Laura D Attardi
10.1038/cr.2013.34
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The FBW7-KLF2 axis regulates endothelial functions

Yongchao Zhao1 and Yi Sun
10.1038/cr.2013.50
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Mouse models uncap novel roles of SSBs

Amanda L Bain, Wei Shi and Kum Kum Khanna
10.1038/cr.2013.63
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REVIEWS

Sirtuin deacetylases in neurodegenerative diseases of aging

Adrianna Z Herskovits and Leonard Guarente
10.1038/cr.2013.70
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ORIGINAL ARTICLES

The mitochondrial genome encodes abundant small noncoding RNAs

Seungil Ro, Hsiu-Yen Ma, Chanjae Park, Nicole Ortogero, Rui Song, Grant W Hennig, Huili Zheng, Yung-Ming Lin, Loredana Moro, Jer-Tsong Hsieh and Wei Yan
10.1038/cr.2013.37
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Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP

Qin Yu, Liyan Hu, Qing Yao, Yongqun Zhu, Na Dong, Da-Cheng Wang and Feng Shao
10.1038/cr.2013.54
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Multipotent stem cells isolated from the adult mouse retina are capable of producing functional photoreceptor cells

Tianqing Li, Michelle Lewallen, Shuyi Chen, Wei Yu, Nian Zhang and Ting Xie
10.1038/cr.2013.48
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FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation

Rui Wang, Yan Wang, Ning Liu, Chunguang Ren, Cong Jiang, Kai Zhang, Su Yu, Yunfei Chen, Hui Tang, Qi Deng, Cong Fu, Yingcong Wang, Rong Li, Mingyao Liu, Weijun Pan and Ping Wang
10.1038/cr.2013.42
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Hypertensive stretch regulates endothelial exocytosis of Weibel-Palade bodies through VEGF receptor 2 signaling pathways

Yan Xiong, Zhenqian Hu, Xiaofan Han, Beibei Jiang, Rongli Zhang, Xiaoyu Zhang, Yao Lu, Chenyang Geng, Wei Li, Yulong He, Yingqing Huo, Masabumi Shibuya and Jincai Luo
10.1038/cr.2013.56
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Dlic1 deficiency impairs ciliogenesis of photoreceptors by destabilizing dynein

Shanshan Kong, Xinrong Du, Chao Peng, Yiming Wu, Huirong Li, Xi Jin, Ling Hou, Kejing Deng, Tian Xu and Wufan Tao
10.1038/cr.2013.59
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LETTERS TO THE EDITOR

Brown adipose tissue transplantation improves whole-body energy metabolism

Xiaomeng Liu, Zongji Zheng, Xiaoming Zhu, Minghui Meng, Lan Li, Yanyan Shen, Qingsheng Chi, Dehua Wang, Zhaoyun Zhang, Chenzhong Li, Yiming Li, Yaoming Xue, John R Speakman and Wanzhu Jin
10.1038/cr.2013.64
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Structural basis for termination of AIM2-mediated signaling by p202

Heng Ru, Xiangmin Ni, Lixia Zhao, Christopher Crowley, Wei Ding, Li-Wei Hung, Neil Shaw, Genhong Cheng and Zhi-Jie Liu
10.1038/cr.2013.52
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Long-term deregulated human hematopoiesis in goats transplanted in utero with BCR-ABL-transduced lin⁻CD34⁺ cord blood cells

Fanyi Zeng, Shu-Zhen Huang, Zhi-Juan Gong, Mei-Jue Chen, Don A Baldwin, Wei Hu, Hui Qian, Jing-bin Yan, Juan Wang, Yan Ping Xiao, Yves Chalandon, Ashley Ringrose, Zhao-Rui Ren, Allen Eaves, Connie Eaves and Xiaoyan Jiang
10.1038/cr.2013.60
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