EDITORIAL

Sanofi-Cell Research outstanding paper award of 2014

Dangsheng Li
10.1038/cr.2015.128
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RESEARCH HIGHLIGHTS

Probing hepatocyte heterogeneity

Ben Z Stanger
10.1038/cr.2015.117
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Gasdermin D: the long-awaited executioner of pyroptosis

Si Ming Man and Thirumala-Devi Kanneganti
10.1038/cr.2015.124
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New tricks from an old dog: Another synaptotoxic fragment from APP

Sheue-Houy Tyan and Edward H Koo
10.1038/cr.2015.125
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aBETting therapeutic resistance by Wnt signaling

Carl G Engelke and Arul M Chinnaiyan
10.1038/cr.2015.127
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ORIGINAL ARTICLES

PTEN regulates RPA1 and protects DNA replication forks

Guangxi Wang, Yang Li, Pan Wang, Hui Liang, Ming Cui, Minglu Zhu, Limei Guo, Qian Su, Yujie Sun, Michael A McNutt and Yuxin Yin
10.1038/cr.2015.115
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Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

Xudong Wu, Ida Holst Bekker-Jensen, Jesper Christensen, Kasper Dindler Rasmussen, Simone Sidoli, Yan Qi, Yu Kong, Xi Wang, Yajuan Cui, Zhijian Xiao, Guogang Xu, Kristine Williams, Juri Rappsilber, Casper Kaae Sønderby, Ole Winther, Ole N Jensen and Kristian Helin
10.1038/cr.2015.121
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Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3

Li-Hua Zhao1,2,*, X Edward Zhou3,*, Wei Yi1,*, Zhongshan Wu1,3,4, Yue Liu1, Yanyong Kang3, Li Hou1,3, Parker W de Waal3, Suling Li1, Yi Jiang1, Adrian Scaffidi5, Gavin R Flematti5, Steven M Smith5,6,7, Vinh Q Lam8, Patrick R Griffin8, Yonghong Wang7, Jiayang Li7, Karsten Melcher1,3 and H Eric Xu1,3
10.1038/cr.2015.122
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A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein

Yan Li, Yuhua Wan, Peipei Liu, Jincun Zhao, Guangwen Lu, Jianxun Qi, Qihui Wang, Xuancheng Lu, Ying Wu, Wenjun Liu, Buchang Zhang, Kwok-Yung Yuen, Stanley Perlman, George F Gao and Jinghua Yan
10.1038/cr.2015.113
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Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients

Lu Wen, Jingyi Li, Huahu Guo, Xiaomeng Liu, Shengmin Zheng, Dafang Zhang, Weihua Zhu, Jianhui Qu, Limin Guo, Dexiao Du, Xiao Jin, Yuhao Zhang, Yun Gao, Jie Shen, Hao Ge, Fuchou Tang, Yanyi Huang and Jirun Peng
10.1038/cr.2015.126
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LETTERS TO THE EDITOR

Implication of cell-in-cell structures in the transmission of HIV to epithelial cells

Chao Ni, Lei Huang, Yuhui Chen, Meifang He, Yazhuo Hu, Siyang Liu, Xiangdong Fang, Jingyun Li, Qiang Sun and Xiaoning Wang
10.1038/cr.2015.119
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Direct conversion of astrocytes into neuronal cells by drug cocktail

Lin Cheng, Longfei Gao, Wuqiang Guan, Jianxin Mao, Wenxiang Hu, Binlong Qiu, Jian Zhao, Yongchun Yu and Gang Pei
10.1038/cr.2015.120
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Loss of the sulfate transporter Slc13a4 in placenta causes severe fetal abnormalities and death in mice

Joanna Rakoczy, Zhe Zhang, Francis Gerard Bowling, Paul Anthony Dawson and David Gordon Simmons
10.1038/cr.2015.100
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