RESEARCH HIGHLIGHTS

mTORC2 is a tyrosine kinase

Xuemin Wang and Christopher G Proud
10.1038/cr.2015.134
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Cancer immunosurveillance: role of patrolling monocytes

Luca Cassetta and Jeffrey W Pollard
10.1038/cr.2015.144
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H1 provides the missing link

Michael SY Huen and Junjie Chen
10.1038/cr.2015.138
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REVIEWS

Multiple amino acid sensing inputs to mTORC1

Mitsugu Shimobayashi and Michael N Hall
10.1038/cr.2015.146
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ORIGINAL ARTICLES

Out of southern East Asia: the natural history of domestic dogs across the world

Guo-Dong Wang, Weiwei Zhai, He-Chuan Yang, Lu Wang, Li Zhong, Yan-Hu Liu, Ruo-Xi Fan, Ting-Ting Yin, Chun-Ling Zhu, Andrei D Poyarkov, David M Irwin, Marjo K Hytönen, Hannes Lohi, Chung-I Wu, Peter Savolainen1 and Ya-Ping Zhang
10.1038/cr.2015.147
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Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds

Junqing Ye, Jian Ge, Xu Zhang, Lin Cheng, Zhengyuan Zhang, Shan He, Yuping Wang, Hua Lin, Weifeng Yang, Junfang Liu, Yang Zhao and Hongkui Deng
10.1038/cr.2015.142
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mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR

Yancun Yin, Hui Hua, Minjing Li, Shu Liu, Qingbin Kong, Ting Shao, Jiao Wang, Yuanming Luo, Qian Wang, Ting Luo and Yangfu Jiang
10.1038/cr.2015.133
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Dicer-independent RNA-directed DNA methylation in Arabidopsis

Dong-Lei Yang, Guiping Zhang, Kai Tang, Jingwen Li, Lan Yang, Huan Huang, Heng Zhang and Jian-Kang Zhu
10.1038/cr.2015.145
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Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

Chang-Lin Li, Kai-Cheng Li, Dan Wu, Yan Chen, Hao Luo, Jing-Rong Zhao, Sa-Shuang Wang, Ming-Ming Sun, Ying-Jin Lu, Yan-Qing Zhong, Xu-Ye Hu, Rui Hou, Bei-Bei Zhou, Lan Bao, Hua-Sheng Xiao and Xu Zhang
10.1038/cr.2015.149
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Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer

Ke Chen, Jing Zhang, Zhongqiang Guo, Qin Ma, Zhengzheng Xu1, Yuanyuan Zhou, Zhiying Xu, Zhongwu Li, Yiqiang Liu, Xiongjun Ye, Xuesong Li, Bifeng Yuan, Yuwen Ke, Chuan He, Liqun Zhou, Jiang Liu and Weimin Ci
10.1038/cr.2015.150
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Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes

Qiaozhen Liu, Rui Yang, Xiuzhen Huang, Hui Zhang, Lingjuan He, Libo Zhang, Xueying Tian, Yu Nie, Shengshou Hu, Yan Yan, Li Zhang, Zengyong Qiao, Qing-Dong Wang, Kathy O Lui and Bin Zhou
10.1038/cr.2015.143
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LETTERS TO THE EDITOR

Parthenogenetic haploid embryonic stem cells efficiently support mouse generation by oocyte injection

Cuiqing Zhong, Zhenfei Xie, Qi Yin, Rui Dong, Suming Yang, Yuxuan Wu, Li Yang and Jinsong Li
10.1038/cr.2015.132
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Birth of fertile bimaternal offspring following intracytoplasmic injection of parthenogenetic haploid embryonic stem cells

Zhikun Li, Haifeng Wan, Guihai Feng, Leyun Wang, Zhengquan He, Yukai Wang, Xiu-Jie Wang, Wei Li, Qi Zhou and Baoyang Hu
10.1038/cr.2015.151
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Generation of macaques with sperm derived from juvenile monkey testicular xenografts

Zhen Liu, Yan-Hong Nie, Chen-Chen Zhang, Yi-Jun Cai, Yan Wang, Hui-Ping Lu, Yu-Zhuo Li, Cheng Cheng, Zi-Long Qiu and Qiang Sun
10.1038/cr.2015.112
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