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Table of Contents

Volume 29 Issue 7, Jul 2019

The impact of intestinal microbes goes well beyond intestine. Molecular signals derived from intestinal microbes can prompt islet beta cells to secrete insulin in a Nod1-dependent manner. When bacteria speak, islet beta cells nod.See page 516-532 by Qin Zhang et al. for details.

RESEARCH HIGHLIGHTS

UIM-UDS: a new interface between ATG8 and its interactors

Yuchen Leiand Daniel J. Klionsky
https://doi.org/10.1038/s41422-019-0179-y
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The insulin receptor goes nuclear

Thiago M. Batista, Carly T. Cederquist and C. Ronald Kahn
https://doi.org/10.1038/s41422-019-0185-0
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RNA binding to p62 impacts selective autophagy

Mohit Misra and Ivan Dikic
https://doi.org/10.1038/s41422-019-0167-2
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Chemical choreography of germinal center B-cell migration

Vu N. Ngo and Markus Müschen
https://doi.org/10.1038/s41422-019-0170-7
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ORIGINAL ARTICLES

Intestinal lysozyme liberates Nod1 ligands from microbes to direct insulin trafficking in pancreatic beta cells

Qin Zhang, Ying Pan, Benhua Zeng, Xiaojiao Zheng, Haifang Wang, Xueying Shen , Hui Li , Qian Jiang, Jiaxu Zhao ,Zhuo-Xian Meng, Pingping Li, Zhengjun Chen , Hong Weiand Zhihua Liu
https://doi.org/10.1038/s41422-019-0190-3
Full Text | PDF | Abstract | Open Access


Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis

Shanhui Liao , Girish Rajendraprasad , Na Wang, Susana Eibes, Jun Gao, Huijuan Yu, Gao Wu, Xiaoming Tu, Hongda Huang,Marin Barisic and Chao Xu
https://doi.org/10.1038/s41422-019-0187-y
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Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis

Fudi Zhong, Zhigao Hu , Keqing Jiang, Biao Lei, Zhan Wu, Guandou Yuan, Hongliang Luo, Chunqiang Dong, Bo Tang,Chaowen Zheng, Shuai Yang, Yonglian Zeng, Zhenya Guo, Shuiping Yu, Huizhao Su, Guo Zhang, Xiaoqiang Qiu,Stephen Tomlinson and Songqing He
https://doi.org/10.1038/s41422-019-0175-2
Full Text | PDF | Abstract | Open Access


BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules

Yuejia Huang, Lin Lin , Xing Liu , Sheng Ye , Phil Y. Yao, Wenwen Wang, Fengrui Yang , Xinjiao Gao, Junying Li,Yin Zhang, Jiancun Zhang, Zhihong Yang, Xu Liu, Zhenye Yang, Jianye Zang, Maikun Teng, Zhiyong Wang, Ke Ruan,Xia Ding , Lin Li , Don W. Cleveland, Rongguang Zhangand Xuebiao Yao
https://doi.org/10.1038/s41422-019-0178-z
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AIF-regulated oxidative phosphorylation supports lung cancer development

Shuan Rao , Laura Mondragón , Blanka Pranjic, Toshikatsu Hanada, Gautier Stoll , Thomas Köcher, Peng Zhang,Alexander Jais, Alexander Lercher, Andreas Bergthaler, Daniel Schramek , Katharina Haigh , Valentina Sica ,Marion Leduc , Nazanine Modjtahedi, Tsung-Pin Pai, Masahiro Onji, Iris Uribesalgo, Reiko Hanad, Ivona Kozieradzki,Rubina Koglgruber, Shane J. Cronin, Zhigang She, Franz Quehenberger, Helmut Popper , Lukas Kenner ,Jody J. Haigh , Oliver Kepp , Malgorzata Rak, Kaican Cai , Guido Kroemer and Josef M. Penninger
https://doi.org/10.1038/s41422-019-0181-4
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LETTERS TO THE EDITOR

Canine transmissible venereal tumor genome reveals ancient introgression from coyotes to pre-contact dogs in North America

Xuan Wang , Bo-Wen Zhou , Melinda A. Yang, Ting-Ting Yin ,Fang-Liang Chen, Sheila C. Ommeh, Ali Esmailizadeh,Melissa M. Turner, Andrei D. Poyarkov, Peter Savolainen,Guo-Dong Wang , Qiaomei Fu and Ya-Ping Zhang
https://doi.org/10.1038/s41422-019-0183-2
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Mitochondrial metabolism and glutamine are essential for mesoderm differentiation of human pluripotent stem cells

Vivian Lu , Perrine Dahan, Fasih M. Ahsan, Alexander N. Patananan, Irena J. Roy, Alejandro Torres Jr., Robert M. T. Nguyen, Dian Huang, Daniel Braas1 and Michael A. Teitell
https://doi.org/10.1038/s41422-019-0191-2
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CORRIGENDA

Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

Wenshuai Li, Xu Zhang, Xingyu Lu, Lei You, Yanqun Song, Zhongguang Luo, Jun Zhang, Ji Nie, Wanwei Zheng, Diannan Xu, Yaping Wang, Yuanqiang Dong, Shulin Yu, Jun Hong, Jianping Shi, Hankun Hao, Fen Luo, Luchun Hua, Peng Wang, Xiaoping Qian, Fang Yuan, Lianhuan Wei, Ming Cui, Taiping Zhang, Quan Liao, Menghua Dai, Ziwen Liu, Ge Chen, Katherine Meckel, Sarbani Adhikari, Guifang Jia, Marc B Bissonnette, Xinxiang Zhang, Yupei Zhao, Wei Zhang, Chuan He and Jie Liu
https://doi.org/10.1038/s41422-019-0182-3
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