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To help the soldiers (T cells) better identify spies (non-self antigens, marked in blue) and protect the city, while avoiding harm to normal citizens (self-antigens, marked in orange), we need to improve the functionalities of two weapons: a blue glove or a blue goggle (T cell receptor, TCR) and a sword or a bow (CD8). Optimization of both weapons and their cooperation will significantly strengthen the soldiers’ power. See page 265–283 by Rui Qin et al. for details.
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Wen Zhang, David Artis
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Yingying Zhang, Jiahuai Han
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Daolin Tang, Rui Kang, Guido Kroemer
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Sofiya Zbaranska, Sheena A. Josselyn
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Zhao Yang, Shu-Hua Zhou, Qi-Yue Zhang, Zhi-Chen Song, Wen-Wen Liu, Yu Sun, Ming-Wei Wang, Xiao-Long Fu, Kong-Kai Zhu, Ying Guan, Jie-Yu Qi, Xiao-Hui Wang, Yu-Nan Sun, Yan Lu, Yu-Qi Ping, Yue-Tong Xi, Zhen-Xiao Teng, Lei Xu, Peng Xiao, Zhi-Gang Xu, Wei Xiong, Wei Qin, Wei Yang, Fan Yi, Ren-Jie Chai, Xiao Yu, Jin-Peng Sun
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Rui Qin, Yong Zhang, Jiawei Shi, Peng Wu, Chenyi An, Zhenhai Li, Nuo Liu, Ziyan Wan, Ting Hua, Xiaolong Li, Jizhong Lou, Weiwei Yin, Wei Chen
https://doi.org/10.1038/s41422-025-01077-9
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Demeng Sun, Xiang Li, Qingning Yua, Yuanxia Wang, Pan Shi, Huanhuan Zhang, Tao Wang, Wenjing Sun, Shenglong Ling, Yuanchun Liu, Jinglin Lai, Wenqin Xie, Wanchao Yin, Lei Liu, H. Eric Xu, Changlin Tian
https://doi.org/10.1038/s41422-025-01095-7
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Yi Li, Paulina Fischer, Mengjiao Wang, Qianxing Zhou, Aixia Song, Rui Yuan, Wanyu Meng, Fei Xavier Chen, Reinhard Lührmann, Benjamin Lau, Ed Hurt, Jingdong Cheng
https://doi.org/10.1038/s41422-025-01084-w
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Li Zhong, Qi Zhang, Ning Lu, Tao Wang, Xiaoli Xue, Zhongjun Qin
https://doi.org/10.1038/s41422-024-01063-7
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Yifei Wang, Yuechan Wang, Hui Yang, Ao Li, Dan Ma, Huaizong Shen
https://doi.org/10.1038/s41422-025-01081-z
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Ran Feng, Feng Liu, Ruofei Li, Zhifen Zhou, Zhuoheng Lin, Song Lin, Shengcheng Deng, Yingying Li, Baoting Nong, Ying Xia, Zhiyi Li, Xiaoqin Zhong, Shuhan Yang, Gang Wan, Wenbin Ma, Su Wu, Zhou Songyang
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